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The detection of antibodies in human and animal filariases by counterimmunioelectrophoresis with Dirofilaria immitis antigens

Published online by Cambridge University Press:  05 June 2009

Robert S. Desowitz  and
Steven R. Una
Robert S. Desowitz
Affiliation:
Department of Tropical Medicine and Medical Microbiology, School of Medicine, University of Hawaii 96816, USA
Steven R. Una
Affiliation:
Department of Tropical Medicine and Medical Microbiology, School of Medicine, University of Hawaii 96816, USA
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Abstract

Counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with Dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. Antigens used in the test were prepared from microfilariae and adult male D. immitis. Some humans and animals had antibodies to both antigens while others had antibodies against microfilariae or adult worms only. The presence of soluble circulating antigen was detected in the sera of two dogs with high microfilaraemias.

Type
Research Article
Information
Journal of Helminthology , Volume 50 , Issue 1 , March 1976 , pp. 53 - 57
Copyright
Copyright © Cambridge University Press 1976

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