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Histopathology of experimental Schistosoma incognitum infection in mice following exposure to normal and irradiated cercariae

Published online by Cambridge University Press:  05 June 2009

H. C. Tewari
Affiliation:
Indian Veterinary Research Institute, Izatnagar, U.P., India
P. K. Ramachandran
Affiliation:
Indian Veterinary Research Institute, Izatnagar, U.P., India

Abstract

The tissue reactions in mice, experimentally infected with normal and irradiated cercariae of S. incognitum were studied. The lesions observed in the skin, liver, lungs and the intestine of mice infected with normal cercariae are briefly described, and compared with those observed with cercariae irradiated at 3000 r of gamma rays. In general, the reactions in mice exposed to normal cercariae were more intense than in those infected with irradiated cercariae. The severity of the reactions appeared largely due to the deposition of eggs in the tissues of the mice infected with normal cercariae. The experimental evidence suggested that most of the flukes from the irradiated cercariae are destroyed in the liver by tissue reaction.

Type
Research Papers
Copyright
Copyright © Cambridge University Press 1979

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