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Studies with Brugia pahangi. 16. Precipitation antibody in infected cats detected by counterimmunoelectrophoresis

Published online by Cambridge University Press:  05 June 2009

R. S. Desowitz ,
P. Oothuman  and
D. A. Denham
R. S. Desowitz
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
P. Oothuman
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
D. A. Denham
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
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Abstract

In cats infected with normal, or irradiated, infective (L3) larvae of Brugia pahangi counterimmunoelectro-phoresis revealed the presence of antibody to soluble antigens derived from microfilariae, adults and infective larvae of the same parasite. Infected cats with a persistently high to moderate microfilaraemia gave positive precipitin reactions to L3, microfilarial and adult worm antigens. Cats which had become amicrofilaraemic had antibody to L3 and microfilarial antigens but not to adult worm antigen. Serum from cats inoculated with irradiated L3 larvae produced a precipitin reaction only to the L3 antigen.

Type
Research Papers
Information
Journal of Helminthology , Volume 52 , Issue 2 , June 1978 , pp. 127 - 130
Copyright
Copyright © Cambridge University Press 1978

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References

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