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Trapping of large numbers of larvae in the livers of Toxocara canis-reinfected mice

Published online by Cambridge University Press:  05 June 2009

Kazuo Sugane  and
Tomoo Oshima
Kazuo Sugane
Affiliation:
Department of Parasitology, School of Medicine, Yokohama City University, Yokohama City, Japan
Tomoo Oshima
Affiliation:
Department of Parasitology, School of Medicine, Yokohama City University, Yokohama City, Japan
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Abstract

Congenially athymic nude mice (BALB/c-nu/nu) and BALB/c-nu/+ were infected with 500 embryonated Toxocara canis eggs. Six weeks later they were reinfected with the same number of eggs. The liver and other organs were examined for numbers of 2nd-stage larvae at 2,4, and 6 weeks after reinfection. Far more larvae were trapped in the liver after reinfection than after the primary infection but fewer were found in the livers of BALB/c-nu/nu than in BALB/c-nu/+ mice.

Type
Research Papers
Information
Journal of Helminthology , Volume 57 , Issue 2 , June 1983 , pp. 95 - 99
Copyright
Copyright © Cambridge University Press 1983

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References

REFERENCES

Beaver, P. C., Snyder, C. H., Carrenra, G. M., Dent, J. H. & Lafferty, J. W. (1952) Chronic eosinophilia due to visceral larva migrans. Report of three cases. Pediatrics, 9, 7–19.CrossRefGoogle ScholarPubMed
Burren, C. H. (1971) The distribution of Toxocara larvae in the central nervous system of the mouse. Transactions of the Royal Society of Tropical Medicine and Hygiene, 65, 450–453.CrossRefGoogle ScholarPubMed
Butterworth, A. E., David, J. R., Franks, D., Mahmoud, A. A. F., David, P. H., Sturrock, R. F. & Houba, V. (1977) Antibody dependent eosinophil-mediated damage to 51Cr-labeled schistosomula of Schistosoma mansoni: Damage by purified eosinophils. Journal of Experimental Medicine, 145, 136–150.CrossRefGoogle Scholar
Kayes, S. G. & Oaks, J. A. (1978) Development of the granulomatous response in murine toxocariasis. American Journal of Pathology, 93, 277–294.Google ScholarPubMed
Olson, L. J. (1962) Organ distribution of Toxocara canis larvae in normal mice previously infected with Toxocara, Ascaris or Trichinella. Texas Reports on Biology and Medicine, 20, 651–657.Google ScholarPubMed
Oshima, T. (1961) Standardization of techniques for infecting mice with Toxicara canis and observations on the normal migration routes of the larvae. Journal of Parasitology, 47, 652–656.CrossRefGoogle Scholar
Oshima, T. (1976) Observations of the age resistance, eosinophilia, and larval behavior in the helminth-free beagles infected with Toxocara canis. Japanese Journal of Parasitology, 25, 447–455.Google Scholar
Phillips, S. M., Diconza, J.J., Gold, J. A. & Reid, W. A. (1977) Schistosomiasis in the congenitally athymic (nude) mouse. 1. Thymic dependency of eosinophilia, granuloma formation and host morbidity. Journal of Immunology, 118, 594–599.CrossRefGoogle Scholar
Sugane, K. & Oshima, T. (1982) Eosinophilia, granuloma formation and migratory behavior of larvae in the congenitally athymic mouse infected with Toxocara canis. Parasite Immunology, 4, 307–318.CrossRefGoogle ScholarPubMed