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Uptake of adenosine 3′, 5′-cyclic monophosphate and isoproterenol by filarial parasites*

Published online by Cambridge University Press:  05 June 2009

Khalid Masood
Affiliation:
Division of Biochemistry and Division of Parasitology, Central Drug Research Institute, Lucknow, India
V. M. L. Srivastava
Affiliation:
Division of Biochemistry and Division of Parasitology, Central Drug Research Institute, Lucknow, India
D. P. Singh
Affiliation:
Division of Biochemistry and Division of Parasitology, Central Drug Research Institute, Lucknow, India
R. K. Chatterjee
Affiliation:
Division of Biochemistry and Division of Parasitology, Central Drug Research Institute, Lucknow, India
A. B. Sen
Affiliation:
Division of Biochemistry and Division of Parasitology, Central Drug Research Institute, Lucknow, India

Abstract

The filarial parasites Litomosoides carinii and Dipetalonema viteae both show transcuticular uptake of adenosine 3′, 5′-cyclic monophosphate but isoproterenol is taken up by D. viteae only. The importance of this difference is discussed from the point of view of metabolic regulation. Inhibition of uptake by lectins indicates the involvement of surface sugar moieties in the transport processes.

Type
Research Papers
Copyright
Copyright © Cambridge University Press 1983

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