Skip to main content Accessibility help

A 15-year retrospective study of 160 cases of benign lip lesions

  • S Arslan (a1), B Çobanoğlu (a2), A Ural (a1), İ Sayğin (a3) and A Ü Işik (a1)...



This study aimed to describe the results of a retrospective analysis of a specific cohort of patients with benign lip lesions encountered in the last 15 years in the School of Medicine at Karadeniz Technical University.


A total of 312 patients were managed for lip lesions during the period 2000–2014. Data from 160 samples of benign lip biopsies were retrieved from the pathology laboratory records.


The study group included 20 different histopathological types of lesions, with mucocele being the most frequent lesion (43.13 per cent). The other frequent lesions were chronic inflammatory infiltrate (11.25 per cent), intradermal naevus (5.63 per cent), pyogenic granuloma (5.63 per cent), fibroma (5 per cent) and papilloma (5 per cent). Mucocele was significantly more common in younger patients (p < 0.001).


Knowledge of the epidemiology and distribution of oral mucosal lesions is essential to promote early diagnosis and treatment. Further epidemiological studies exploring the causal relationships and risk factors for lip lesions are necessary for a better understanding of lip diseases.


Corresponding author

Address for correspondence: Dr Selçuk Arslan, Tıp Fakültesi, Karadeniz Teknik Üniversitesi, KBB AD, Kalkınma M. 61080, Trabzon, Turkey Fax: +90 462 325 0518 E-mail:


Hide All
1Osterne, RL, Costa, FW, Mota, MR, Vidal Patrocínio, RM, Alves, AP, Soares, EC et al. Lip lesions in a Brazilian population. J Craniofac Surg 2011;22:2421–5
2Ntomouchtsis, A, Karakinaris, G, Poulolpoulos, A, Kechagias, N, Kittikidou, K, Tsompanidou, C et al. Benign lip lesions. A 10-year retrospective study. Oral Maxillofac Surg 2010;14:115–18
3Espinoza, I, Rojas, R, Aranda, W, Gamonal, J. Prevalence of oral mucosal lesions in elderly people in Santiago, Chile. J Oral Pathol Med 2003;32:571–5
4Furlanneto, DL, Crighton, A, Topping, GV. Differences in methodologies of measuring the prevalence of oral mucosal lesions in children and adolescents. Int J Paediatr Dent 2006;16:31–9
5Shulman, JD, Beach, MM, Rivera-Hidalgo, F. The prevalence of oral mucosal lesions in U.S. adults. Data from the Third National Health and Nutrition Examination Survey, 1988–1994. J Am Dent Assoc 2004;135:1279–86
6Torres-Domingo, S, Bagan, JV, Jimenez, Y, Poveda, R, Murillo, J, Díaz, JM et al. Benign tumors of the oral mucosa: a study of 300 patients. Med Oral Patol Oral Cir Bucal 2008;13:E1616
7Al-Khateeb, TH. Benign oral masses in a Northern Jordanian population–a retrospective study. Open Dent J 2009;28:147–53
8Bermejo, A, Aguirre, JM, Lopez, P, Saez, MR. Superficial mucocele: report of 4 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;88:469–72
9Yamasoda, T, Tayama, N, Syoji, M, Fukuta, M. Clinicostatistical study of lower lip mucoceles. Head Neck 1990;12:316–20
10Bouquot, JE, Gundlach, K. Oral exophytic lesions in 23,616 white Americans over 35 years of age. Oral Surg Oral Med Oral Pathol 1986;62:284–91
11Chi, AC, Lambert, PR 3rd, Richardson, MS, Neville, BW. Oral mucoceles: a clinicopathologic review of 1,824 cases, including unusual variants. J Oral Maxillofac Surg 2011;69:1086–93
12Cohen, L. Mucoceles of the oral cavity. Oral Surg Oral Med Oral Pathol 1965;19:365–72
13Robinson, L, Hjorting-Hansen, E. Pathologic changes associated with mucous retention cysts of minor salivary glands. Oral Surg Oral Med Oral Pathol 1964;18:191205
14Harrison, JD. Salivary mucoceles. Oral Surg Oral Med Oral Pathol 1975;39:268–78
15Oliveira, DT, Consolaro, A, Freitas, FJ. Histopathological spectrum of 112 cases of mucocele. Braz Dent J 1993;4:2936
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *



Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed