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The Rhinoconjunctivitis Quality of Life Questionnaire and its modified short version validation in adults and children with allergic rhinitis

Published online by Cambridge University Press:  01 December 2021

P Katsimpris ,
G Tripsianis ,
A Printza ,
E Giotakis ,
E Simopoulos ,
J Constantinidis  and
M Katotomichelakis
P Katsimpris
Affiliation:
Department of Otorhinolaryngology, Democritus University of Thrace, Alexandroupolis, Greece
G Tripsianis
Affiliation:
Department of Statistics, Democritus University of Thrace, Alexandroupolis, Greece
A Printza
Affiliation:
First Department of Otorhinolaryngology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece
E Giotakis
Affiliation:
First Department of Otorhinolaryngology, Hippocration Hospital, National and Kapodistrian University of Athens, Athens, Greece
E Simopoulos
Affiliation:
Department of Otorhinolaryngology, Democritus University of Thrace, Alexandroupolis, Greece
J Constantinidis
Affiliation:
First Department of Otorhinolaryngology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece
M Katotomichelakis*
Affiliation:
Department of Otorhinolaryngology, Democritus University of Thrace, Alexandroupolis, Greece
*
Author for correspondence: Prof M Katotomichelakis, Department of Otorhinolaryngology, Alexandroupolis University Hospital, Dragana, Alexandroupolis68100, Greece E-mail: mkatotom@med.duth.gr
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Abstract

Objective

This study aimed to develop the Greek versions of the Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire for adult and pediatric populations, discuss their differences and detect the impact of age and gender on quality of life questionnaire results.

Method

Ninety-eight patients with allergic rhinitis participated. Quality of Life evaluation was made by two generic (Short Form-36 and Beck Depression Inventory) and two disease-specific questionnaires (Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire). Symptom evaluation was made by the Total 5 Symptoms Score assessment.

Results

Internal consistency and test–retest reliability of both questionnaires was high. Convergent validity showed statistically significant negative correlations of total Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire with overall Short Form-36 Health Survey score and positive correlations with Beck Depression Inventory and Total 5 Symptoms Score. Discriminative validity demonstrated statistically significant improvement for all instruments and all domains after treatment. Females presented highly significant increased scores. Patient age was positively correlated with total scores of Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire. The clinically significant improvement after treatment was higher among females than males, while it was independent of patient age.

Conclusion

Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire proved to be valid and reliable methods of assessment of allergic rhinitis-related quality of life in children, adolescents and adults.

Keywords

Allergic RhinitisQuality of LifeChildren
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 4 , April 2022 , pp. 341 - 348
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Prof M Katotomichelakis takes responsibility for the integrity of the content of the paper

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