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Acquired nasopharyngeal stenosis in a patient with sarcoidosis

  • J R Brodsky (a1), S A Tatum (a1) and R T Kelley (a1)
Abstract
Abstract Introduction:

Acquired nasopharyngeal stenosis typically occurs as a result of surgery or irradiation of the nasopharynx. Sarcoidosis has numerous manifestations in the head and neck region, although an association with nasopharyngeal stenosis has not previously been reported.

Case report:

A 40-year-old man with sarcoidosis developed severe acquired nasopharyngeal stenosis. This was successfully managed with balloon dilatation, followed by pharyngoplasty with local pharyngeal flap reconstruction.

Conclusion:

This report is intended to prompt consideration of nasopharyngeal stenosis as a potential cause of nasal obstruction in patients with sarcoidosis, and to draw attention to the need to consider sarcoidosis in the differential diagnosis of patients with acquired nasopharyngeal stenosis. We also demonstrate the viability of pharyngoplasty in the management of nasopharyngeal stenosis in the setting of sarcoidosis.

Copyright
Corresponding author
Address for correspondence: Dr Jacob R Brodsky, Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, 300 Longwood Avenue, Lo-367Boston, MA02115 Fax: +781 216 3155 E-mail: jacob.brodskyj@childrens.harvard.edu
Footnotes
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Presented as a poster at the Triological Society Meeting at the Combined Otolaryngological Sections Meeting, 29 April to 1 May 2010, Las Vegas, Nevada, USA

Footnotes
References
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1 NN Chheda , GN Postma . Balloon dilation of an acquired nasopharyngeal stenosis. Otolaryngol Head Neck Surg 2009;140:939–41

3 YP Krespi , A Kacker . Management of nasopharyngeal stenosis after uvulopalatoplasty. Otolaryngol Head Neck Surg 2000;123:692–5

4 E Toh , AW Pearl , EM Genden , W Lawson , ML Urken . Bivalved palatal transposition flaps for the correction of acquired nasopharyngeal stenosis. Am J Rhinol 2000;14:199204

5 LM Jones , VL Guillory , EA Mair . Total nasopharyngeal stenosis: treatment with laser excision, nasopharyngeal obturators, and topical mitomycin-C. Otolaryngol Head Neck Surg 2005;133:795–8

6 MC Iannuzzi , BA Rybicki , AS Teirstein . Sarcoidosis. N Engl J Med 2007;357:2153–65

7 A Lazarus . Sarcoidosis: epidemiology, etiology, pathogenesis, and genetics. Dis Mon 2007;55:649–60

8 JJ Braun , A Gentine , G Pauli . Sinonasal sarcoidosis: review and report of fifteen cases. Laryngoscope 2004;114:1960–3

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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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