Hostname: page-component-848d4c4894-ttngx Total loading time: 0 Render date: 2024-06-11T01:00:08.296Z Has data issue: false hasContentIssue false
  • English
  • Français

Atypical carcinoid of larynx: presentation with scalp metastases

Published online by Cambridge University Press:  29 June 2007

Cosme Ereño ,
Jose I. Lopez  and
Jose M. Sanchez
Cosme Ereño*
Affiliation:
Department of Pathology, Hospital de Basurto, Basque Country University, Bilbao, Spain.
Jose I. Lopez
Affiliation:
Department of Pathology, Hospital de Basurto, Basque Country University, Bilbao, Spain.
Jose M. Sanchez
Affiliation:
Department of Otolaryngology, Hospital de Basurto, Basque Country University, Bilbao, Spain.
*
Address for correspondence: Dr Cosme Ereño, Dept. de Anatomia Patologica Hospital de Basurto, Avda. de Montevideo 18, 48013 Bilbao, Spain.
Get access Rights & Permissions [Opens in a new window]

Abstract

A case of atypical carcinoid tumour of the larynx in a 72-year-old woman is presented. The neoplasm was located in the supraglottic region and was first manifest by metastases to the scalp. The presence of amyloid-like material and calcitonin-positive cells were features that resembled medullary carcinoma of the thyroid. Clinically, it pursued an aggressive course that led to death 58 months after diagnosis. The literature is reviewed, particularly that regarding the differential diagnosis.

Keywords

Laryngeal neoplasmsCarcinoid tumourNeoplasm metastasisScalp
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 1 , January 1997 , pp. 89 - 91
Copyright
Copyright © JLO (1984) Limited 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Batsakis, J. G., El-Naggar, A. K., Luna, M. A. (1992) Neuroendocrine tumors of the larynx. Annals of Otology, Rhinology and Laryngology 101: 710–714.Google Scholar
El-Naggar, A. K., Batsakis, J. G., Vassilopoulou-Sellin, R., Ordoñez, N. G., Luna, M. A. (1991) Medullary (thyroid) carcinoma-like carcinoids of the larynx. Journal of Laryngology and Otology 105: 683–686.Google Scholar
Ferlito, A., Milroy, C. M., Barnes, L., Wenig, B. M., Silver, C E. (1995) Laryngeal paraganglioma versus atypical carcinoid tumour. Annals of Otology, Rhinology and Laryngology 104: 78–83.CrossRefGoogle Scholar
McCluggage, W. G., Bharucha, H., Cameron, C. H. S., Toner, P. G. (1994) Amphicrine carcinoma of the larynx. Histopathology 24: 182–185.CrossRefGoogle ScholarPubMed
Milroy, C. M., Rode, J., Moss, E. (1991) Laryngeal paragangliomas and neuroendocrine carcinomas. Histopathology 18: 201–209.CrossRefGoogle ScholarPubMed
Smeets, G., Warson, F., Dehou, M. F., Storme, G., Sacre, R., Van Belle, S., Somers, G., Gepts, W., Kloppel, G. (1990) Metastasizing neuroendocrine carcinoma of the larynx with calcitonin and somatostatin secretion and CEA production, resembling medullary thyroid carcinoma. Virchow's Archives (Pathologic Anatomy) 416: 539–543.CrossRefGoogle Scholar
Sweeney, E. C., McDonnell, L., O'Brien, C. (1981) Medullary carcinoma of the thyroid presenting as tumours of the pharynx and larynx. Histopathology 5: 263–275.Google Scholar
Wick, M. R., Millns, J. L., Sibley, R. K., Pittelkow, M. R., Winkelmann, R. K. (1985) Secondary neuroendocrine carcinomas of the skin. An immunohistochemical comparison with primary neuroendocrine carcinoma of the skin (‘Merkel cell’ carcinoma). Journal of the American Academy of Dermatology 13: 134–142.CrossRefGoogle ScholarPubMed
Woodruff, J. M., Senie, R. T. (1991) Atypical carcinoid tumor of the larynx. A critical review of the literature. Journal of Otorhinolaryngology and Related Specialties 53: 194–209.Google Scholar
Zambruno, G., Bertazzoni, M. G., Botticelli, A., Manca, V., Giannetti, A. (1989) Carcinome neuro-endocrine du larynx avec métastases cutanées. Annales de Dermatologie et Venereologie 116: 855–858.Google Scholar