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Detection of hepatitis B virus in the cerumen of patients with chronic hepatitis B infection

  • A Eftekharian (a1), H Moghaddasi (a1), L Gachkar (a2) and S S A Amlashi (a1)

To investigate hepatitis B virus DNA in the cerumen of hepatitis B virus infected patients.


This study comprised 30 confirmed cases of chronic hepatitis B. Patients' serum samples were examined for hepatitis B surface antigen and antibodies using enzyme immunoassay systems. The presence of hepatitis B virus DNA in cerumen was investigated using a polymerase chain reaction test.


All of the samples were positive for hepatitis B surface antigen and negative for hepatitis B surface antibodies. Hepatitis virus DNA was detected in two cerumen samples (6.6 per cent of patients).


Cerumen can be a potential source of transmission of hepatitis B virus.

Corresponding author
Address for correspondence: Dr A Eftekharian, Department of Otorhinolaryngology, Loghman Hospital, Kamali Ave, Kargar, 13336-31151 Tehran, Iran Fax: +98,-21-55416170 E-mail:
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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