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Does gestational diabetes result in cochlear damage?

Published online by Cambridge University Press:  17 November 2014

A Selcuk ,
H Terzi ,
U Turkay ,
A Kale  and
S Genc
A Selcuk*
Affiliation:
ENT Clinic, Derince Education and Research Hospital, Kocaeli, Turkey
H Terzi
Affiliation:
Gynecology and Obstetric Clinic, Derince Education and Research Hospital, Kocaeli, Turkey
U Turkay
Affiliation:
Gynecology and Obstetric Clinic, Derince Education and Research Hospital, Kocaeli, Turkey
A Kale
Affiliation:
Gynecology and Obstetric Clinic, Derince Education and Research Hospital, Kocaeli, Turkey
S Genc
Affiliation:
ENT Clinic, Derince Education and Research Hospital, Kocaeli, Turkey
*
Address for correspondence: Dr A Selcuk, ENT Clinic, Derince Education and Research Hospital, 41100 Kocaeli, Turkey Fax: +90 2622335540 E-mail: sadin27@yahoo.com
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Abstract

Background:

Glucose metabolism has a significant impact on inner-ear physiology. Therefore, hearing may be affected in gestational diabetes.

Method:

A matched case–control study was performed to evaluate 27 patients with gestational diabetes and 31 non-diabetic pregnant women with similar demographic characteristics. A medical history was taken for each participant, and otological inspections and high-frequency audiometry tests were performed.

Results:

There were no significant differences in average pure tone air–bone hearing thresholds between the groups (p > 0.05). However, evaluation of high-frequency hearing thresholds indicated significantly increased auditory thresholds at 10 kHz and 12 kHz for right ears and at 8, 10, 12 and 14 kHz for left ears in the gestational diabetes group (p < 0.001).

Conclusion:

An investigation into cochlear damage in gestational diabetic patients showed significant high-frequency hearing loss. Further studies are needed to validate these findings in different ethnic groups and geographical populations.

Keywords

Diabetes, GestationalCochlear Hearing Loss
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 11 , November 2014 , pp. 961 - 965
Copyright
Copyright © JLO (1984) Limited 2014 

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References

1Maia, CA, Campos, CA. Diabetes mellitus as etiological factor of hearing loss. Braz J Otorhinolaryngol 2005;71:208–14CrossRefGoogle ScholarPubMed
2Davis, H, Silverman, RS. Hearing and Deafness, 3rd edn.New York: Holt, Rinehart & Wilson, 1970:253–79Google Scholar
3Silman, S, Silverman, CA. Auditory Diagnosis, Principles and Applications. 1st edn.London: Singular Publishing Group, 1991Google Scholar
4Hong, O, Buss, J, Thomas, E. Type 2 diabetes and hearing loss. Dis Mon 2013;59:139–46CrossRefGoogle ScholarPubMed
5Inzucchi, SE, Bergenstal, RM, Buse, JB, Diamant, M, Ferrannini, E, Nauck, M. American Diabetes Association (ADA) European Association for the Study of Diabetes (EASD) Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012;35:1364–79CrossRefGoogle Scholar
6Harris, MI. Classification, diagnostic criteria and screening for diabetes. In: Aubert, RE. Diabetes in America, 2nd edn.National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, NIH Publication No. 95-1468, 1995:15–35Google Scholar
7Bellamy, L, Casas, JP, Hingorani, AD. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet 2009;23:1773–9Google Scholar
8Kim, C, Newton, KM, Knopp, RH. Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care 2002; 25:1862–8Google Scholar
9Summary and recommendations of the Second International Workshop Conference on Gestational Diabetes Mellitus. Diabetes 1985;34(Suppl 2):123–6CrossRefGoogle Scholar
10Mayfield, JA, Deb, P, Potter, DEB. Diabetes and long-term care. In: Aubert, RE. Diabetes in America, 2nd edn.National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, NIH Publication No. 95-1468, 1995:571–90Google Scholar
11Akinpelu, OV, Mujica-Mota, M, Daniel, SJ. Is type 2 diabetes mellitus associated with alterations in hearing? A systematic review and meta-analysis. Laryngoscope 2014;124:767–76Google Scholar
12Ozel, HE, Ozkiriş, M, Gencer, ZK, Saydam, L. Audiovestibular functions in noninsulin-dependent diabetes mellitus. Acta Otolaryngol 2014;134:51–7CrossRefGoogle ScholarPubMed
13Biurrun, O, Ferrer, JP, Lorente, J, España, R, Gomis, R, Traserra, J. Asymptomatic eletronystagmographic abnormalities in patients with type I diabetes mellitus. ORL J Otorhinolaryngol Relat Spec 1991;5:335–8Google Scholar
14Aladag, I, Eyibilen, A, Güven, M, Atiş, O, Erkokmaz, U. Role of oxidative stress in hearing impairment in patients with type two diabetes mellitus. J Laryngol Otol 2009;123:957–63Google Scholar
15Frisina, ST, Mapes, F, Kim, S, Frisina, DR, Frisina, RD. Characterization of hearing loss in aged type II diabetics. Hear Res 2006;211:103–13Google Scholar
16Nagle, C, Skouteris, H, Morris, H, Nankervis, A, Rasmussen, B, Mayall, P et al. Primary prevention of gestational diabetes for women who are overweight and obese: a randomised controlled trial. BMC Pregnancy Childbirth 2013;13:65CrossRefGoogle Scholar
17Clausen, TD, Mathiesen, ER, Hansen, T, Pedersen, O, Jensen, DM, Lauenborg, J et al. Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes. J Clin Endocrinol Metab 2009;94:2464–70Google Scholar