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Head and neck sarcomas: clinical and histopathological presentation, treatment modalities, and outcomes

  • M Stavrakas (a1), I Nixon (a1), K Andi (a1), R Oakley (a1), J P Jeannon (a1), A Lyons (a2), M McGurk (a2), T Guerrero Urbano (a3), S Thavaraj (a4) and R Simo (a1)...
Abstract
Abstract Background:

Sarcoma of the head and neck is a rare condition that poses significant challenges in management and often requires radical multimodality treatment.

Objectives:

This study aimed to analyse current clinical presentation, evaluation, management dilemmas and oncological outcomes.

Methods:

Computer records and case notes were analysed, and 39 patients were identified. Variables were compared using Pearson's chi-square test and the log-rank test, while survival outcomes were calculated using the Kaplan–Meier method.

Results:

The histopathological diagnosis was Kaposi sarcoma in 20.5 per cent of cases, chondrosarcoma in 15.3 per cent and osteosarcoma in 10.2 per cent. A range of other sarcomas were diagnosed in the remaining patients. The site of disease was most commonly sinonasal, followed by the oral cavity and larynx.

Conclusion:

Wide local excision with clear resection margins is essential to achieve local control and long-term survival. There is a need for cross-specialty collaboration in order to accrue the evidence which will be necessary to improve long-term outcomes.

Copyright
Corresponding author
Address for correspondence: Dr Marios Stavrakas, Department of Otorhinolaryngology Head and Neck Surgery, 3rd Floor Southwark Wing, Guy's Hospital, St Thomas Street, London SE1 9RT, UK E-mail: mstavrakas@doctors.org.uk
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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