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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Kirsche, H. and Klimek, L. 2015. ASS-Intoleranz-Syndrom und persistierende Rhinosinusitis. HNO, Vol. 63, Issue. 5, p. 357.

    Kirsche, Hanspeter Pfaar, Oliver Olze, Heidi and Förster, Ulrike 2013. Analgetikaintoleranz. Allergo Journal, Vol. 22, Issue. 1, p. 33.

    Roth, Douglas and Ferguson, Berrylin J 2010. Vocal allergy: recent advances in understanding the role of allergy in dysphonia. Current Opinion in Otolaryngology & Head and Neck Surgery, Vol. 18, Issue. 3, p. 176.

    Szczeklik, Andrzej Niżankowska-Mogilnicka, Ewa and Sanak, Marek 2009. Middleton's Allergy: Principles and Practice.


Laryngeal edema as the only symptom of hypersenitivity to salicylic acid and other substances

  • G. Hillerdal (a1) and H. Lindholm (a2)
  • DOI:
  • Published online: 01 June 2007

Idiosyncrasy to salicylic acid and related substances is well known, the most common symptoms being asthma, rhinorrhea and urticaria. We here describe two cases whose only symptoms were hoarseness and in which inspection revealed laryngeal edema when the patients ingested any of these substances. In cases of chronic recurring hoarseness, a history should be taken with respect to such hypersensitivity and suspect cases should be challenged, since a strict diet may improve the symptoms.

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G. A. Settipane , and R. K. Pudupakkam (1975) Aspirin intolerance. III. Subtypes, familial occurrence and cross-reactivity with tartrazine. Journal of Allergy and Clinical Immunology, 56: 215221.

B. Stenius and M. Lemola (1976) Hypersensitivity to acetylsalicylic acid (ASA) and tartrazine in patients with asthma. Clinical Allergy, 6: 119129.

A. Szczeklik , R. J. Gryglewski , and G. Czerniawska-Mysik (1975) Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma-attacks in aspirin-sensitive patients. British Medical Journal, 1: 6769.

A. Szczeklik , R. J. Gryglewski and G. Czerniawska-Mysik (1977) Clinical patterns of hypersensitivity to non-steroidal anti-inflammatory drugs and their pathogenesis. Journal of Allergy and Clinical Immunology 60: 276284.

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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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