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Macrocytosis and sudden sensorineural hearing loss: a case report

  • A E L McMurran (a1) and R A Adair (a1)
Abstract
Background:

Although other blood dyscrasias are known to cause sudden sensorineural hearing loss, macrocytosis has not previously been implicated in the absence of another causative agent.

Case report:

We present a case of bilateral sequential sudden sensorineural hearing loss in a patient with significant macrocytosis (mean corpuscular volume at presentation 124 fl) secondary to alcohol-induced liver dysfunction.

Conclusion:

A possible pathophysiological mechanism linking macrocytosis and sudden sensorineural hearing loss was identified, suggesting areas for further investigation.

Copyright
Corresponding author
Address for correspondence: Ms A E L McMurran, Department of Otolaryngology, Ulster Hospital, Upper Newtownards Road, Dundonald, Belfast BT16 1RH, Northern Ireland, UK E-mail: aelmcmurranacademic@gmail.com
Footnotes
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Presented as an oral presentation at the Royal Academy of Medicine in Ireland Otolaryngology Winter Meeting, 12 December 2014, Dublin, Ireland

Footnotes
References
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2Freeman, SRM, Bray, ME, Amos, CS, Gibson, WPR. The association of codeine, macrocytosis and bilateral sudden or rapidly progressive sensorineural deafness. Acta Otolaryngol 2009;129:1061–6
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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