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Primary laryngeal lymphoma in China: a retrospective study of the last 25 years

  • P Zhao (a1), Y Zhou (a2) and J Li (a1)

Abstract

Objective

To retrospectively study the primary laryngeal lymphoma cases in China reported in Chinese-language literature.

Method

Chinese-language literature was searched for papers on primary laryngeal lymphoma published in the last 25 years.

Results

The selected papers comprised a total of 115 cases. The male-to-female ratio was 3.4:1. Non-Hodgkin's lymphoma was the exclusive pathological type. The estimated 3-year, 5-year and 10-year survival rates were 70.9 ± 6.4 per cent, 63.4 ± 7.6 per cent and 56.4 ± 9.5 per cent respectively, as determined by Kaplan–Meier analysis. B-cell non-Hodgkin's lymphoma patients had a better prognosis than T-cell non-Hodgkin's lymphoma patients (p = 0.032). Patients with lymph node involvement at diagnosis had a poorer prognosis (p < 0.01).

Conclusion

Primary laryngeal lymphoma is a rare disease with no specific clinical features. More than one biopsy might be needed to obtain the correct diagnosis. Proper treatment could lead to promising outcomes. The T-cell subtype and lymph node involvement at diagnosis might indicate worse prognosis.

Copyright

Corresponding author

Author for correspondence: Dr Jinrang Li, Department of Otolaryngology, Navy General Hospital, No. 6 Fucheng Road, Haidian District, Beijing, China E-mail: entljr@sina.com Fax: +86 010 6695 8034

Footnotes

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Dr J Li takes responsibility for the integrity of the content of the paper

Footnotes

References

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