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Radiotherapy in head and neck cancer management: United Kingdom National Multidisciplinary Guidelines

  • C Nutting (a1)
Abstract
Abstract

This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. Radiotherapy is one of the key treatment modalities used in head and neck cancer management. This paper summarises the current role and some of the recent advances in radiotherapy in head and neck cancer management.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Corresponding author
Address for correspondence: Chris Nutting, Head and Neck Unit, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK E-mail: chris.nutting@rmh.nhs.uk
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2. CM Nutting , JP Morden , KJ Harrington , TG Urbano , SA Bhide , C Clark Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. Lancet Oncol 2011;12:127–36

3. MK Kam , SF Leung , B Zee , RM Chau , JJ Suen , F Mo Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients. J Clin Oncol 2007;25:4873–9

5. JP Pignon , A le Maitre , E Maillard , J Bourhis , M-NC. Group Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol 2009;92:414

8. JA Bonner , PM Harari , J Giralt , RB Cohen , CU Jones , RK Sur Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival. Lancet Oncol 2010;11:21–8

9. J Bernier , C Domenge , M Ozsahin , K Matuszewska , JL Lefèbvre , RH Greiner Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004;350:1945–52

10. JS Cooper , Q Zhang , TF Pajak , AA Forastiere , J Jacobs , SB Saxman Long-term follow-up of the RTOG 9501/intergroup phase III trial: postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 2012;84:1198–205

11. MR Posner , DM Hershock , CR Blajman , E Mickiewicz , E Winquist , V Gorbounova Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N Engl J Med 2007;357:1705–15

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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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