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Use of acellular dermal matrices in laryngotracheal and pharyngeal reconstruction: systematic review

  • A Hui (a1), P Hong (a2) and M Bezuhly (a3)
Abstract
Abstract Background:

Acellular dermal matrices are increasingly used in laryngotracheal and pharyngeal reconstruction, but specific indications and the type of acellular dermal matrix used vary. The authors systematically reviewed outcomes relating to acellular dermal matrix use in head and neck reconstruction.

Methods:

Electronic databases were searched through 1 May 2016 for literature on acellular dermal matrix use in laryngotracheal and pharyngeal reconstruction. Studies were appraised for surgical indications, outcomes and study design.

Results:

Eleven publications with 170 cases were included. Eight articles reported on acellular dermal matrix use in oncological reconstruction. Most studies were case series; no high-level evidence studies were identified. Graft extrusion was more common in non-oncological applications. In general, post-oncological reconstruction with an acellular dermal matrix demonstrated complication rates similar to those reported without an acellular dermal matrix.

Conclusion:

Evidence in support of acellular dermal matrix use in head and neck reconstruction is generally poor. Prospective comparative studies are required to define the indications, safety and effectiveness of acellular dermal matrices in laryngotracheal and pharyngeal reconstruction.

Copyright
Corresponding author
Address for correspondence: Dr Michael Bezuhly, Division of Plastic and Reconstructive Surgery, IWK Health Centre, Dalhousie University, 5850/5980 University Avenue, PO Box 9700, Halifax, Nova Scotia B3K 6R8, Canada Fax: +1 902 470 7939 E-mail: mbezuhly@dal.ca
References
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1 S Pushpoth , K Tambe , S Sandramouli . The use of AlloDerm in the reconstruction of full-thickness eyelid defects. Orbit 2008;27:337–40

2 VG Ortega , D Sastoque . New and successful technique for the management of Parry-Romberg syndrome's soft tissue atrophy. J Craniofac Surg 2005;26:e50710

3 JW Hudson , DO Pickett . A 5-year retrospective review of primary palatoplasty cases utilizing an acellular collagen interpositional graft. J Oral Maxillofac Surg 2015;73:1393

4 DS Haynes , JD Vos , RF Labadie . Acellular allograft dermal matrix for tympanoplasty. Curr Opin Otolaryngol Head Neck Surg 2015;13:283–6

5 JM Gryskiewicz . Dorsal augmentation with AlloDerm. Semin Plast Surg 2008;22:90103

6 W Wang , JC Fan , CJ Sun , Y Chen , HW Zhao , H Ma Systematic evaluation on the use of acellular dermis matrix graft in prevention Frey syndrome after parotid neoplasm surgery. J Craniofac Surg 2013;24:1526–9

7 AW Pearl , P Woo , R Ostrowski , J Mojica , DL Mandell , P Costantino . A preliminary report on micronized AlloDerm injection laryngoplasty. Laryngoscope 2002;112:990–6

9 C Lisi , MJ Hawkshaw , RT Sataloff . Viscosity of materials for laryngeal injection: a review of current knowledge and clinical implications. J Voice 2013;27:119–23

10 M Remacle , G Lawson . Results with collagen injection into the vocal folds for medialization. Curr Opin Otolaryngol Head Neck Surg 2007;15:148–52

11 JM King , CB Simpson . Modern injection augmentation for glottic insufficiency. Curr Opin Otolaryngol Head Neck Surg 2007;15:153–8

12 SA Aldekhayel , H Sinno , MS Gilardino . Acellular dermal matrix in cleft palate repair: an evidence-based review. Plast Reconstr Surg 2012;130:177–82

13 JE Losee , DM Smith . Acellular dermal matrix in palatoplasty. Aesthet Surg J 2012;31:S10815

14 C Kucur , K Durmus , R Gun , MO Old , A Agrawal , TN Teknos Safety and efficacy of concurrent neck dissection and transoral robotic surgery. Head Neck 2015;38:e51923

15 GZ Cheng , E Folch , R Brik , S Gangadharan , P Mallur , JH Wilson Three-dimensional modeled T-tube design and insertion in a patient with tracheal dehiscence. Chest 2015;148:e1068

16 DA Kelly , C Plikatitis , D Blalock , LC Argenta , LR David . AlloDerm revision for failed pharyngoplasty. J Craniofac Surg 2012;23:645–9

18 L Zhang , JP Cheng , WC Zhang , W Li , M Anniko . Reconstruction of defects following surgery for hypopharyngeal carcinoma using artificial biological material. Acta Otolaryngol 2010;130:1293–9

19 UK Sinha , KE Chang , CW Shih . Reconstruction of pharyngeal defects using AlloDerm and sternocleidomastoid muscle flap. Laryngoscope 2001;111:1910–16

20 AP Sclafani , AA Jacono , JN Dolitsky . Grafting of the peritonsillar fossa with an acellular dermal graft to reduce posttonsillectomy pain. Am J Otolaryngol 2001;22:409–14

21 P Li , S Li , Q Tang , X He , D Yin , S Wang Reconstruction of human oncological tracheal defects with xenogenic acellular dermal matrix. Auris Nasus Larynx 2017;44:237–40

22 J He , Y Tian , P Wu , L Liao , H Quan , J Kang Heterogeneous bovine acellular dermal matrix for mucosal repair in reconstructive surgery for laryngeal and hypopharyngeal carcinoma. Oncol Res Treat 2015;38:282–4

23 D Yin , Q Tang , S Wang , S Li , X He , J Liu Xenogeneic acellular dermal matrix in combination with pectoralis major myocutaneous flap reconstructs hypopharynx and cervical esophagus. Eur Arch Otorhinolaryngol 2015;272:3457–61

24 P Persichetti , A Aveta , F Segreto . Combined use of acellular dermal matrix and supraclavicular artery island flap for oropharyngeal reconstruction. Plast Reconstr Surg 2013;131:641e–2e

25 C Piazza , V Taglietti , P Nicolai . Reconstructive options after total laryngectomy with subtotal or circumferential hypopharyngectomy and cervical esophagectomy. Curr Opin Otolaryngol Head Neck Surg 2012;20:7788

26 AP Kontos , Z Qian , NS Urato , A Hassanein , SA Proper . AlloDerm grafting for large wounds after Mohs micrographic surgery. Dermatol Surg 2009;35:692–8

27 DA Girod , K Sykes , J Jorgensen , O Tawfik , T Tsue . Acellular dermis compared to skin grafts in oral cavity reconstruction. Laryngoscope 2009;119:2141–9

28 ES Chiu , PL Friedlander . Reply: combined use of acellular dermal matrix and supraclavicular artery island flap for oropharyngeal reconstruction. Plast Reconstr Surg 2013;131:642e–3e

29 LJ Shi , Y Wang , C Yang , WW Jiang . Application of acellular dermal matrix in reconstruction of oral mucosal defects in 36 cases. J Oral Maxillofac Surg 2012;70:e58691

30 HZ Ibrahim , TJ Kwiatkowski , KT Montone , SM Evans , D Rosenthal , AA Chalian Effects of external beam radiation on the allograft dermal implant. Otolaryngol Head Neck Surg 2000;122:189–94

31 MG Dubin , M Feldman , HZ Ibrahim , R Tufano , SM Evans , D Rosenthal Allograft dermal implant (AlloDerm) in a previously irradiated field. Laryngoscope 2000;110:934–7

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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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