Mental disorder of a very simple kind may be often traced to the frequent repetition of some slight cause of irritation, the repetition having the most injurious effect. The effect of a constant or constantly recurring cause of disturbance may be seen to produce not only the simpler forms of mental disorder, but may also be recognised as a true cause of the gravest form of nervous disease. The mind may be upset, just as the temper may be ruined, by slight domestic worries; and this disturbance of mind may be followed by disease of the brain. In my experience, the brain is destroyed in general paralytics more frequently by constant causes of excitement or anxiety and worry, than by any sudden injury or shock.
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