The author has investigated the relative development of the superficial or molecular layer of the cortex of the cerebrum and of the cerebellum in a number of animals and in normal and abnormal human beings. For comparative purposes he takes what he terms the “index of the molecular layer,” meaning thereby the ratio of that layer to the whole thickness of the cortex taken as 100. The central sections examined were from the middle part of the second frontal convolution in the human subjects, from the convolutions bordering the cruciform sulcus in the dogs, and in the other animals from the anterior part of the cerebrum. About twenty indices were taken in each case, and the mean of these indices was then calculated. The subjects included represented a very varied choice, including two frogs, a snake, nine fowls, two pigeons, a mole, numerous dogs, some of them epileptic, a monkey, etc. The human subjects comprised a number of normal individuals of either sex and of different ages, as well as groups of epileptics, criminals, and patients suffering from various forms of in sanity. The results are given in a summarised form for each case.
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