At considerable length the author points ont that early writers on general paralysis have either quite omitted, or but casually dwelt on, the eye symptoms of the disease. Thus in the works of Esquirol, Bayle, Calmeil, Delaye, Forille père, Daveau, Thore, &c., but little importance is attached to these symptoms. In 1849 M. Baillarger observed that many patients have one pupil larger than the other, the difference in some cases being so great that it is astonishing that this observation had not been made sooner. This symptom sometimes exists from the beginning of the disease, and may now, in doubtful cases, aid in diagnosis; generally, however, it is not seen till an advanced period.
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