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The Relation of Focal Infection to Mental Disease

  • Nicholas Kopeloff (a1) and George H. Kirby (a1)

The recent contributions of Hunter (1) and Moynihan (2) are significant of the importance of focal infection or “sepsis” in mental disease. Cotton's (3) view that toxæmia resulting from focal infection is the specific cause of the “functional” psychoses is well known on both sides of the Atlantic. Further, his therapeutic claims for surgical detoxication are only too familiar.

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1 Hunter, W., “Chronic Sepsis as a Cause of Mental Disorder. I. Relation of Focal Sepsis to Mental Disease,” Brit. Med. Journ., No. 3487, November 5, 1927, pp. 811814; Journ. Ment. Sci., lxxiii, 1927, pp. 549-563.
2 Moynihan, B. Sir, II. Relation of Aberrant Mental States to Organic Disease,” Brit. Med. Journ., pp. 815817.
3 Cotton, H. A., The Defective, Delinquent, and Insane, Princeton University Press, 1921.
4 Kopeloff, N., and Cheney, C. O., “Studies in Focal Infection : Its Presence and Elimination in the Functional Psychoses,” Amer. Journ. Psychiat., ii, No. 2, October, 1922, pp. 139156.
5 Kopeloff, N., and Kirby, G. H., “Focal Infection and Mental Disease,” Amer. Journ. Psychiat., iii, No. 2, October, 1923, pp. 149192.
6 Hunter, W., Brit. Med. Journ., No. 3487, November 5, 1927, p. 818; Journ. Ment. Sci., lxxiii, 1927, p. 726.
7 Kopeloff, N., Lactobacillus acidophilus, Williams & Wilkins, Co., Baltimore, Md., 1926.
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The British Journal of Psychiatry
  • ISSN: 0368-315X
  • EISSN: 2514-9946
  • URL: /core/journals/the-british-journal-of-psychiatry
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The Relation of Focal Infection to Mental Disease

  • Nicholas Kopeloff (a1) and George H. Kirby (a1)
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