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A forward planned treatment planning technique for non-small-cell lung cancer stereotactic ablative body radiotherapy based on a systematic review of literature

Published online by Cambridge University Press:  26 August 2015

Anne C. Marchant
Affiliation:
North Wales Cancer Treatment Centre, Department of Medical Physics, Bodelwyddan, UK Faculty of Health & Wellbeing, Sheffield Hallam University, Sheffield, UK
Sheela M. Macwan*
Affiliation:
Faculty of Health & Wellbeing, Sheffield Hallam University, Sheffield, UK
*
Correspondence to: Anne Marchant, North Wales Cancer Treatment Centre, Glan Clwyd Hospital, North Wales, LL18 5UJ, UK. Tel: 01745 7830 (7353). Email: Anne.Marchant@wales.nhs.uk

Abstract

Purpose and Method

A systematic literature review of six computerised databases was undertaken in order to review and summarise a forward planned lung stereotactic ablative body radiotherapy (SABR) treatment planning (TP) technique as a starting point for clinical implementation in the author’s department based on current empirical research. The data were abstracted and content analysed to synthesise the findings based upon a SIGN quality checklist tool.

Findings

A four-dimensional computed tomography scan should be performed upon which the internal target volume and organs at risk (OAR) are drawn. A set-up margin of 5 mm is applied to account for inter-fraction motion. The field arrangement consists of a combination of 7–13 coplanar and non-coplanar beams all evenly spaced. Beam modifiers are used to assist in the homogeneity of the beam, although a 20% planning target volume dose homogeneity is acceptable. The recommended fractionations by the UK SABR Consortium are 54 Gy in 3 fractions (standard), 55–60 Gy in 5 fractions (conservative) and 50–60 Gy in 8–10 fractions (very conservative). Conformity indices for both the target volume and OAR will be used to assess the planned distribution.

Conclusion

An overview of a clinically acceptable forward planned lung SABR TP technique based on current literature as a starting point, with a view to inverse planning with support from the UK SABR Consortium mentoring scheme.

Type
Literature Review
Copyright
© Cambridge University Press 2015 

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