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Choroidal metastases: case report and review

Published online by Cambridge University Press:  29 December 2020

Victor Duque Open the ORCID record for Victor Duque [Opens in a new window] ,
Carolina de la Pinta ,
Ciriaco Corral ,
Carmen Vallejo ,
Margarita Martin ,
Raul Hernanz ,
Elsa Margarita Mezherane ,
Lira Pelari ,
Antonio Hernandez  and
Mireia Valero
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Victor Duque
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Carolina de la Pinta
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Ciriaco Corral
Affiliation:
Ophtalmology Department, Ramon y Cajal University Hospital, Madrid, Spain
Carmen Vallejo
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Margarita Martin
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Raul Hernanz
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Elsa Margarita Mezherane
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Lira Pelari
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Antonio Hernandez
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Mireia Valero
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
Sonsoles Sancho
Affiliation:
Radiation Oncology Department, Ramon y Cajal University Hospital, Madrid, Spain
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Abstract

Introduction:

Choroidal metastases are the most frequent intraocular secondary tumours, with a prevalence of 2–7% according to the literature. Our aim was to review a clinical case of choroidal metastasis.

We present a case of a 63-year-old male patient diagnosed in 2018 with lung adenocarcinoma cT4N0M1. The patient had three metastases in the brain, which were successfully treated with radiosurgery (RS). The patient was treated with chemotherapy with pemetrexed–cisplatin schedule. Five months after diagnosis, the patient presented with decreased vision in the right eye. After ophthalmologic evaluation, he was diagnosed with a right choroidal metastasis, which was treated with external beam radiotherapy with 20 Gy in five fractions, resulting in improved visual acuity and a complete clinical and radiological response.

The patient took part in a clinical trial that continued with systemic chemotherapy. Twenty-two months after radiotherapy to the eye, the patient has good visual acuity without any side effects.

Conclusions:

Choroidal metastasis treated with radiotherapy achieves good local control, with limited side effects, allowing an improvement in visual acuity and consequently, an improvement in the patient´s quality of life.

Keywords

choroidal metastasisintraocular tumourradiotherapyradiation therapySBRT
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 21 , Issue 2 , June 2022 , pp. 215 - 221
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Copyright
© The Author(s), 2020. Published by Cambridge University Press

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