Skip to main content Accessibility help
×
×
Home

Comparison of conformal radiotherapy, intensity-modulated radiotherapy and tomotherapy irradiation techniques in prostate cancers

  • Taylan Tuğrul (a1), Nezahat Olacak (a2) and Murat Köylü (a2)

Abstract

Aim

The aim of this study is to compare three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT) and tomotherapy techniques used in the treatment of prostate cancer with target and critical organ doses to be included.

Materials and Methods

The target dose was studied with 4-and 6-field 3D-CRT, 7-field IMRT and tomotherapy techniques used to treat ten patients for prostate cancer and the dose volume histograms of critical organs were analyzed. The same target volumes, critical organs doses prescribed and treatment times for the three techniques were compared. Total dose of 76 Gy was given using 6 MV and 18 MV for 3D-CRT, 6 MV for IMRT and tomotherapy techniques.

Results

When we compare the three techniques, for rectum V35(p:0·001), V65(p:0·001), D50(p:0·020) and D25(p:0·002), for bladder V50(p:0·027), V65(p:0·006), V100(p:0·006) and for femoral head, the V50(p:0·001) dose was found to be significantly different and more favourable in the tomotherapy technique. Significant differences were found with IMRT planning in 50% of bladder volume (p:0·002). There is no significant difference between the three techniques for doses of 100% volume of rectum and 25% of volume of bladder. The minimum dose that healthy tissue received which was outside the tumour volume was investigated.

Findings

Doses to critical organs were lower using the tomotherapy technique. However, the minimum doses that healthy tissue received were higher for the tomotherapy technique. When the beam on times were compared for all three techniques, a significant difference was found in favor of tomotherapy.

Copyright

Corresponding author

Author for correspondence: Murat Köylü, Department of Radiation Oncology, Faculty of Medicine, Ege University, Izmir, Turkey. Tel: +905058794458. E-mail: ismubil81@gmail.com

Footnotes

Hide All

Cite this article: Tuğrul T, Olacak N, Köylü M. (2019) Comparison of conformal radiotherapy, intensity-modulated radiotherapy and tomotherapy irradiation techniques in prostate cancers. Journal of Radiotherapy in Practice page 1 of 4. doi: 10.1017/S1460396918000766

Footnotes

References

Hide All
1. Baltimore, M D. Report on the management of clinically localized prostate cancer. J Urol 1995: 249253.
2. Battermann, J J. I-125 implantation for localized prostate cancer: the Utrecht University Experience. Radiother Oncol 2000; 57: 269272.
3. Ispir, B. Quality Control of intensity modulated Radiotherapy Planning in Prostate Cancer Treatment and Comparison of Dose Distribution with 3-D Conformal Radiotherapy. Master thesis 2010, Hacettepe University, Ankara.
4. Malone, S. Dose-escaleted 3D conformal radiotherapy in prostate cancer. Expert Rev Anticancer Ther 2004; 4 (4): 663668.
5. Wolff, D, Stieler, F, Welzel, G. A volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer. Radiother Oncol 2009; 93: 226233.
6. Balog, J, Soisson, E. Helical tomotherapy quality assurance. Int J Radiation Oncology Biol. Phys 2008; 71 (1): 113117.
7. Gunhan, B. Comparison of dosimetric methods of Delivery Quality Assurance (DQA) in Helical Tomotherapy. İstanbul University, Institute of Health Sciences, Fundamental Oncology PhD Thesis, 2010, İstanbul.
8. Mackie, T R, Olivera, G H, Kapatoes, J M, et al. Helical Tomotherapy. AAPM 2003, Wisconsin, United Kingdom.
9. Zelefsky, M J, Valicenti, R, Hunt, M, Perez, C A. Low-risk prostate cancer. Perez and Brady’s Principles and Practice of Radiation Oncology, 5th edn. Philadelphia, USA: Lippincott Williams and Wilkins, 2008.
10. Michalski, J, Purdy, J, Bruner, D W , et al. RTOG 0126 A phase III randomized study of high dose 3D-CRT/IMRT versus standard dose 3D-CRT/IMRT in patients treated for localized prostate cancer. NRG Oncology 2008. United States of America.
11. Ramsey, CR, Scaperoth, D, Seibert, R. et al. Image-guided helical tomotherapy for localized prostate cancer: technique and initial clinical observations. J Appl Clin Med Phys 2007; 8 (2320): 3751.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Journal of Radiotherapy in Practice
  • ISSN: 1460-3969
  • EISSN: 1467-1131
  • URL: /core/journals/journal-of-radiotherapy-in-practice
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed