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Dosimetric comparison of helical tomotherapy using different techniques, simultaneous integrated boost and sequential boost for craniospinal irradiation: a single institution experience

Published online by Cambridge University Press:  23 March 2017

Bongkot Jia-Mahasap ,
Imjai Chitapanarux ,
Ekkasit Tharavichitkul ,
Somvilai Chakrabandhu ,
Pitchayaponne Klunklin ,
Wimrak Onchan ,
Anirut Watcharawipha ,
Somsak Wanwilairat  and
Patrinee Traisathit
Bongkot Jia-Mahasap*
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Imjai Chitapanarux
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Ekkasit Tharavichitkul
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Somvilai Chakrabandhu
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Pitchayaponne Klunklin
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Wimrak Onchan
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Anirut Watcharawipha
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Somsak Wanwilairat
Affiliation:
Department of Radiology, The Division of Therapeutic Radiology and Oncology Faculty of Medicine CMU, Mueang, Chiang Mai, Thailand
Patrinee Traisathit
Affiliation:
Department of Statistics, Faculty of Science, CMU, Mueang, Chiang Mai, Thailand
*
Correspondence to: Bongkot Jia-Mahasap, Department of Radiology, Faculty of Medicine, CMU, 110 Intawaroros Road, SriPoom, Mueang, Chiang Mai, Thailand. Tel: 053-945456. Fax: 053-945491. E-mail: phung_nemo@hotmail.com
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Abstract

Purpose

Craniospinal irradiation (CSI) has become an important and challenging radiation technique for radiation oncologists. Helical tomotherapy (HT) seems to have dosimetric advantage for CSI compared with other radiation modalities. The purpose of this study was to compare dosimetric data between two different HT plans; simultaneous integrated boost (SIB) and sequential boost (Sq).

Method

Twelve previously treated CSI contoured datasets by SIB technique were replanned. Dosimetric comparative parameters of targets were conformity index (CI) and homogeneity index (HI). For organ at risk (OARs), the mean dose of parallel organs, D2% of serial organs and whole body integral dose (ID) were also investigated.

Result

SIB plan significantly provided more conformed dose to CSI and tumour boost while resulting in a similar CI in spinal boost region compared with Sq plan. The HI showed no differences between two plans. Radiation exposure to serial organs and ID were also significantly lower in SIB plan.

Conclusion

CSI treatment using HT, SIB technique was feasible and had more target coverage while minimising the radiation dose to healthy tissues.

Keywords

craniospinal irradiationdosimetric comparisonhelical tomotherapy
Type
Original Articles
Information
Journal of Radiotherapy in Practice , Volume 16 , Issue 3 , September 2017 , pp. 245 - 250
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Copyright
© Cambridge University Press 2017 

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