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Small cell lung cancer metastatic to the submandibular gland

Published online by Cambridge University Press:  04 August 2014

Talha Shaikh ,
Hormoz Ehya  and
Aruna Turaka
Talha Shaikh
Affiliation:
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
Hormoz Ehya
Affiliation:
Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA, USA
Aruna Turaka*
Affiliation:
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
*
Correspondence to: Aruna Turaka, Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA. Tel: 215 728 3022. Fax: 215 214 1629. E-mail: Aruna.Turaka@fccc.edu
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Abstract

A 58-year Caucasian woman with a 45-pack year smoking history underwent a computed tomography (CT) scan of the chest due to a persistent respiratory infection. Imaging revealed extensive mediastinal and hilar lymphadenopathy on the right. Fine needle aspiration of the right paratracheal and subcarinal lymph nodes revealed small cell lung carcinoma. She was treated with definitive concurrent chemoradiation (with Cisplatin and Etoposide) therapy to the primary tumor and the mediastinum using intensity modulated radiation therapy. Post-treatment repeat CT of the chest showed complete radiographic response and she was offered prophylactic cranial irradiation which the patient refused. Within six months of completing treatment, the patient developed brain metastases and was treated with a course of palliative radiation to the whole brain. One month after completion, she noticed painful swelling of the left submandibular gland and a CT showed an enlarged submandibular gland. FNA revealed metastatic SCLC. She was treated with urgent palliative RT to the left submandibular gland with significant improvement in her symptoms.

Keywords

small cell lung cancersubmandibular glandpalliativewhole brain radiation therapy
Type
Case Study
Information
Journal of Radiotherapy in Practice , Volume 14 , Issue 1 , March 2015 , pp. 84 - 87
Copyright
© Cambridge University Press 2014 

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