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High-Speed Photography of Human Trabecular Bone during Compression

Published online by Cambridge University Press:  01 February 2011

Philipp J. Thurner ,
Blake Erikson ,
Zachary Schriock ,
John Langan ,
Jeff Scott ,
Maria Zhao ,
Georg E. Fantner ,
Patricia Turner ,
Johannes H. Kindt  and
Georg Schitter
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Philipp J. Thurner
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
Blake Erikson
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
Zachary Schriock
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
John Langan
Affiliation:
Computational Sensors Corp., Santa Barbara, CA, USA
Jeff Scott
Affiliation:
Computational Sensors Corp., Santa Barbara, CA, USA
Maria Zhao
Affiliation:
Computational Sensors Corp., Santa Barbara, CA, USA
Georg E. Fantner
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
Patricia Turner
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
Johannes H. Kindt
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
Georg Schitter
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
Paul K. Hansma
Affiliation:
University of California Santa Barbara, Santa Barbara, CA, USA
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Abstract

The mechanical properties of healthy and diseased bone tissue are extensively studied in mechanical tests. Most of this research is motivated by the immense costs of health care and social impacts due to osteoporosis in post-menopausal women and the aged. Osteoporosis results in bone loss and change of trabecular architecture, causing a decrease in bone strength. To address the problem of assessing local failure behavior of bone, we combined mechanical compression testing of trabecular bone samples with high-speed photography. In this exploratory study, we investigated healthy, osteoarthritic, and osteoporotic human vertebral trabecular bone compressed at high strain rates simulating conditions experienced in individuals during falls. Apparent strains were found to translate to a broad range of local strains. Moreover, strained trabeculae were seen to whiten with increasing strain. We hypothesize that the effect seen is due to microcrack formation in these areas, similar to stress whitening seen in synthetic polymers. From the results of a motion energy filter applied to the recorded movies, we saw that the whitened areas are, presumably, also of high deformation. We believe that this method will allow further insights into bone failure mechanisms, and help toward a better understanding of the processes involved in bone failure.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 874: Symposium l – Structure and Mechanical Behavior of Biological Materials , 2005 , L1.2
Copyright
Copyright © Materials Research Society 2005

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