Hostname: page-component-76fb5796d-9pm4c Total loading time: 0 Render date: 2024-04-25T14:21:44.932Z Has data issue: false hasContentIssue false
  • English
  • Français

Areas of Need for Future Biomaterials Research

Published online by Cambridge University Press:  22 February 2011

J. E. Lemons
J. E. Lemons*
Affiliation:
Ph.D., Professor and Chairman, Department of Biomaterials, University of Alabama at Birmingham, Birmingham, Alabama 35294
Get access

Abstract

Clinical treatment modalities have undergone very significant changes over the past 30 years, in part because of the development of new or improved synthetic substances (biomaterials) for the replacement of tissues. Most all aspects of medical care have been directly influenced. It is now possible to obtain biomaterials made from basic metallic, ceramic, carbonitic, or polymeric materials where the substance has been manufactured for a specific biomedical application. In past years, this was not possible and available industrial grade materials were often adapted or modified to accommodate applications in biological environments. These developments, along with the many other advances in both biomedical sciences and clinical applications, have provided an exciting situation with regard to the improvement of existing prostheses and materials or the development of new biomaterials for surgical implant devices. This presentation will summarize eight areas where defined needs for active biomaterials research continues, following an outline theme of: (1) the current clinical situation; (2) specific area of need; and (3) possible improvements through basic science and clinical research.

This thematic presentation will consider the following general areas: (1) the minimization of interfacial wear and implant biodegradation with examples of total joint replacements and occlusal surfaces of teeth; (2) adhesives for soft and hard tissues with examples of total joint replacements, cements, cardiovascular and plastic surgery reconstructions; (3) percutaneous devices for orthopaedic, dental, cardiovascular, and general surgery; (4) bone and skin replacements for the treatment of major bone lesions and burns; (5) ligaments and tendons for joint and hand reconstructions; (6) spinal instruments for orthopaedic procedures; (7) conduits of various diameters for general and cardiovascular applications; and (8) valves for cardiovascular and urological procedures.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 55: Symposium G – Biomedical Materials , 1985 , 127
Copyright
Copyright © Materials Research Society 1986

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Willert, H.G., Buchhorn, G., and Buchhorn, U., Implant Retrieval: Material and Biological Analysis, NBS Special Publication 601, 239, (1981).Google Scholar
2. Williams, D.F., Biocompatibility of Clinical Implant Materials 1, (CRC Press, Boca Raton, FL, 1981).Google Scholar
3. Woodman, J.L., Orth. Res. Soc. Trans. 6, 166 (1981).Google Scholar
4. Leinfelder, K.F., Soc. for Biomat. Trans., Keynote 8, 166 (1985).Google Scholar
5. Hall, C.W., Cox, P.A., and McFarland, S.R., JBMR 18, 383 (1984).Google Scholar
6. Bodine, R.L., Vakay, L.R., Sullivan, D.Y., Lund, D.F., and Yanase, R.T., J. Oral Impl. 8, No. 2, 193 (1977).Google Scholar
7. Urry, D.W. and Prasad, K.U., Biomcompatibility of Natural Tissues and Their Synthetic Analogs, Williams, D.F., Ed., (CRC Press, Boca Raton, FL, 1986).Google Scholar
8. Feenstra, L. and DeGroot, K., Bioceramics of Calcium Phosphate, DeGroot, K., Ed., (CRC Press, Boca Raton, FL, 1983).Google Scholar
9. Urist, M.R., Hudak, R., Huo, Y., Rasmussen, J., Hirota, W., The Chemistry and Biology of Mineralized Tissues, Butler, W.T., Ed., Conf. Vol., (Ebsco Media Inc., Birmingham, Al, 1984).Google Scholar
10. Noyes, F.R. and McGinness, G.H., Clinc. Ortho. and Rel. Res. 198, 61, (1985).Google Scholar
11. Brand, P.W., Hand Surgery, Ed 3, Flynn, J.E., Ed., (Williams and Wilkins, Baltimore, MD, 1982).Google Scholar
12. Ward, J.J., Nasca, R.J., Lemons, J.E., and Bidez, M. W., Biomedical Engineering III, Recent Developments, Sheppard, L.C., Ed., (Pergamon Press, NY, NY, 1984) p. 168.Google Scholar
13. Wesolow, A., present volume, p.Google Scholar
14. Hoffman, A.S., present volume, p.Google Scholar