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Biocompatible luminescent nanoparticles on the basis of calcium phosphate

  • Sofia Dembski (a1), Moritz Milde (a1), Emeline Dassonneville (a1), Carsten Gellermann (a1), Torsten Klockenbring (a2), Marcel Dyrba (a3) and Stefan Schweizer (a3) (a4)...

Luminescent lanthanide doped SiO2/Hydroxylapatite (HAp) core/shell nanoparticles (NPs) were synthesized by sol-gel technology. The resulting NPs exhibited an amorphous SiO2 core and a crystalline luminescent shell. The formation of the HAp layer was possible at pH 8.5. The characterization of the resulting NPs was done by transmission electron microscopy, X-ray diffraction analysis, inductively-coupled plasma combined with optical emission spectrometry, and photoluminescence spectroscopy. Additionally, the newly developed SiO2/HAp:Ln3+ core/shell NPs were tested for their biocompatibility, e. g. by an in vitro cell culture based assay.

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MRS Online Proceedings Library (OPL)
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  • EISSN: 1946-4274
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