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  • Ana B. Castro-Ceseña (a1), Ekaterina Novitskaya (a2), Po-Yu Chen (a2), M. del Pilar Sánchez-Saavedra (a1), Gustavo Hirata (a3) and Joanna McKittrick (a2)...

Cortical and cancellous bones were demineralized and deproteinized using 1 N HCl and 6% NaOCl, respectively. Experiments were performed at 37°C. The rate constants were calculated and the structural features of untreated and completely demineralized and deproteinized samples were studied by scanning electron microscopy, showing that intact, contiguous structures were obtained. For both cases, the rate constant was higher for cancellous bone than the cortical bone.

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1.Chakkalakal, D. A., Strates, B. S., Garvin, K. L., Novak, J. R., Fritz, E. D., Moliner, T. J. and McGuire, M. H.. Tissue Eng. 7, 161 (2001).
2.Mauney, J. R., Jaquiéry, C., Volloch, V., Heberer, M., Martin, I. and Kaplan, D. L.. Biomater. 26, 3173 (2005).
3.Li, X., Jin, L., Balian, G., Laurencin, C. T. and Anderson, D. G.. Biomater. 27, 2426 (2006).
4.Wang, Z.-H., He, X.-J., Yang, Z.-Q. and Tu, J.-B.. Artif. Organs. 34, 161 (2010).
5.Dodds, R.A., York-Ely, A.M., Zhukauskas, R., Arola, T., Howell, J., Hartill, C., Cobb, R.R. and Fox, C.. J. Biomater. Appl. 25, 195 (2010).
6.Benke, D., Olah, A. and Möhler, H.. Biomaterials. 22, 1005 (2001).
7.Carter, D. H., Scully, A. J., Heaton, D. A., Young, M. P. J., and Aaron, J. E.. Bone. 31, 389 (2002).
8.Stavropoulos, A. and Karring, T.. J. Clin. Periodontol. 37, 200 (2010).
9.Lakes, R.. Nature 361, 511 (1993).
10.Rho, J-Y., Kuhn-Spearing, L. and Zioupos, P.. Med. Eng. Phys. 20, 92 (1998).
11.Weiner, S. and Wagner, H. D.. Annu. Rev. Mater. Sci. 28, 271 (1998).
12.Chen, P.-Y., Lin, A. Y. M., Lin, Y.-S., Seki, Y., Stokes, A.G., Peyras, J., Olevsky, E. A., Meyers, M.A. and McKittrick, J.. J. Mech. Behav. Biomed. Mater. I, 208 (2008).
13.Birkedal-Hansen, H.. J. Histochem. Cytochem. 22, 428 (1974).
14.Birkedal-Hansen, H.. J. Histochem. Cytochem. 22, 434 (1974).
15.Castro-Ceseña, A.B., Novitskaya, E.E., Chen, P.-Y., Hirata, G.A., and McKittrick, J.. Mat. Sci. Eng. C. (2010) doi: 10.1016/j.msec.2010.11.003.
16.Termine, J. D., Eanes, E. D., Greenfield, D. J., Nylen, M. U. and Harbor, R. A.. Calc. Tiss. Res. 12, 73 (1973).
17.Broz, J. J., Simske, S. J., Corley, W. D. and Greenberg, A. R.. J. Mater. Sci. - Mater. Med. 8, 395 (1997).
18.Fantner, G. E., Hassenkam, T., Kindt, J. H., Weaver, J. C., Birkedal, H., Pechenik, L., Cutroni, J. A., Cidade, G. A., Stuky, G. D., Morse, D. E. and Hansma, P. K.. Nat. Mater. 4, 612 (2005).
19.Thurner, P. J., Erickson, B., Turner, P., Jungmann, R., Lelujian, J., Proctor, A., Weaver, J. C., Schitter, G., Morse, D. E. and Hansma, P. K.. Adv. Mater. 21, 451 (2009).
20.Lowry, O. H., Rosebrough, N. J., Farr, A. l. and Randall, R. J.. J. Biol. Chem. 193, 265 (1951).
21.Bigi, A., Cojazzi, G., Panzavolta, S., Ripamonti, A., Roveri, N., Romanello, M., Noris Suarez, K. and Moro, L.. J. Inorg. Biochem. 68, 45 (1997).
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