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Detection of Organophosphate Gases and Biological Molecules using Embedded Piezoresistive Microcantilever Sensors

  • Tim L Porter (a1), Tim Vail (a2) and Richard J Venedam (a3)

Abstract

Embedded piezoresistive microcantilever (EPM) sensors have been used in the detection of a variety of analyte species. EPM sensors utilize a tiny piezoresistive microcantilever partially embedded into a sensing material to produce a sensing element that is compact, simple, resistant to movement and shock, and suitable for remote sensing applications. In the current project, we have used sensing materials comprised of an immobilizing polymer functionalized with either target enzymes or antibodies to detect two biological agents, Bacillus subtilis and Diisopropyl fluorophosphate (DFP). DFP is used as a simulant for organophosphate nerve agents, while BG is a large bacterial spore used as a simulant for other bacterial spores such as bacillus anthracis. Sensing results are presented for both types of EPM sensors.

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References

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1 Porter, T.L., et al., An Embedded Polymer Piezoresistive Microcantilever Sensor. Ultramicroscopy, 2003. 97: p. 365369.
2 Porter, T.L., et al., Sensor Based on Piezoresistive Microcantilever Technology. Sensors and Actuators, 2001. A88: p. 4751.
3 Kooser, A., et al., Investigation of the Antigen Antibody Reaction Between Anti-Bovine Serum Albumin and Bovine Serum Albumin Using Piezorsistive Microcantilever Sensors. Biosensors and Bioelectronics, 2003. 19: p. 503508.
4 Gunter, R.L., et al., Viral Detection Using an Embedded Piezoresistive Microcantilever Sensor. Sensors and Actuators (A), 2003. A107: p. 219224.
5 Porter, T.L., et al., Viral Detection Using an Embedded Piezoresistive Microcantilever Sensor. Sensors and Actuators (A), 2003. 107(3): p. 219224.
6 Kooser, A., et al., Gas Sensing Using Embedded Piezoresistive Microcantilever Sensors. Sensors and Actuators, 2004. 99(2-3): p. 430433.
7 Porter, T.L., et al., A solid-state sensor platform for the detection of hydrogen cyanide gas. Sensors and Actuators, 2007. 123: p. 313317.
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MRS Online Proceedings Library (OPL)
  • ISSN: -
  • EISSN: 1946-4274
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