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Failure of bone at the sub-lamellar level using in situ AFM-SEM investigations

Published online by Cambridge University Press:  30 March 2012

Ines Jimenez-Palomar  and
Asa H. Barber
Ines Jimenez-Palomar
Affiliation:
Department of Materials, School of Engineering and Materials Science Queen Mary University of London Mile End Road, London E1 4NS, United Kingdom.
Asa H. Barber
Affiliation:
Department of Materials, School of Engineering and Materials Science Queen Mary University of London Mile End Road, London E1 4NS, United Kingdom.
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Abstract

In this paper we examine the mechanical properties of individual lamellae from bone material using novel atomic force microscopy (AFM)-scanning electron microscopy (SEM) techniques. Individual lamellar beams were selected from bone using focussed ion beam (FIB) microscopy and mechanically deformed with the AFM while observing failure modes using SEM. Both the elastic and fracture behavior of the bone lamellae were determined using these techniques.

Keywords

fracturebonemicrostructure
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1424: Symposium SS – Properties and Processes at the Nanoscale Nanomechanics of Material Behavior , 2012 , mrsf11-1424-ss04-05-oo03-05
Copyright
Copyright © Materials Research Society 2012

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References

REFERENCES

[1] Fratzl, P. and Weinkamer, R., “Nature’s hierarchical materials,” Progress in Materials Science, vol. 528, pp. 1263–1334, 2007.Google Scholar
[2] Peterlik, H., Roschger, P., Klaushofer, K., and Fratzl, P., “From Brittle To Ductile Fracture Of Bone,” Nature Materials vol. 5, pp. 52–55, 2006.Google Scholar
[3] Gupta, H. S. and Zioupos, P., “Fracture Of Bone Tissue: The ‘Hows’ And The ‘Whys’,” Medical Engineering & Physics vol. 30, pp. 1209–1229, 2008.Google Scholar
[4] Yang, Q. D., Cox, B. N., Nalla, R. K., and Ritchie, R. O., “Re-Evaluating The Toughness Of Human Cortical Bone,” Bone, vol. 38, pp. 878–887, 2006.Google Scholar
[5] Rho, J. Y., Currey, J. D., Zioupos, P., and Pharr, G., “The Anisotropic Young’s Modulus Of Equine Secondary Osteones And Interstitial Bone Determined By Nanoindentation,” The Journal of Experimental Biology, vol. 204, pp. 1775–1781, 2001.Google Scholar
[6] Gupta, H. S., Stachewicz, U., and Wagermaier, W., “Mechanical modulation at the lamellar level in osteonal bone,” J. Mater. Res., vol. 21, pp. 1913–1921, 2006.Google Scholar
[7] Rho, J. Y., Tsui, T. Y., and Pharr, G. M., “Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation,” Biomaterials, vol. 18, pp. 1325–1330, 1997.Google Scholar
[8] Jimenez-Palomar, I., Shipov, A., Shahar, R., and Barber, A. H., “Influence of SEM vacuum on bone micromechanics using in situ AFM,” Journal of the Mechanical Behavior of Biomedical Materials, 2011.Google Scholar
[9] Hang, F., Lu, D., Bailey, R. J., Jimenez-Palomar, I., Stachewicz, U., Cortes-Ballesteros, B., Davies, M., Zech, M., Bödefeld, C., and Barber, A. H., “In situ tensile testing of nanofibers by combining atomic force microscopy and scanning electron microscopy,” Nanotechnology, vol. 22, 2011.Google Scholar
[10] Hang, F. and Barber, A. H., “Nano-mechanical properties of individual mineralized collagen fibrils from bone tissue,” J. R. Soc. Interface, vol. 857, pp. 500–505, 2011.Google Scholar
[11] Liu, D., Weiner, S., and Wagner, D., “Anisotropic mechanical properties of lamellar bone using miniature cantilever bending specimens,” Journal of Biomechanics, vol. 2, pp. 647–654, 1999.Google Scholar
[12] Ritchie, R. O., Koester, K. J., Ionova, S., Yaoc, W., Lane, N. E., and Ager, J. W. III, “Measurement Of The Toughness Of Bone: A Tutorial With Special Reference To Small Animal Studies,” Bone, vol. 43, pp. 798–812, 2008.Google Scholar