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Label Free DNA Detection Using Large Area Graphene-Based FET Biosensors

Published online by Cambridge University Press:  20 May 2011

Shirui Guo ,
Jian Lin ,
Miroslav Penchev ,
Emre Yangel ,
Mihrimah Ozkan  and
Cengiz S. Ozkan
Shirui Guo
Affiliation:
Department of Chemistry, University of California, Riverside, 92521
Jian Lin
Affiliation:
Department of Mechanical Engineering, University of California, Riverside, 92521
Miroslav Penchev
Affiliation:
Department of Electrical Engineering, University of California, Riverside, 92521
Emre Yangel
Affiliation:
Department of Electrical Engineering, University of California, Riverside, 92521
Mihrimah Ozkan
Affiliation:
Department of Chemistry, University of California, Riverside, 92521 Department of Electrical Engineering, University of California, Riverside, 92521
Cengiz S. Ozkan
Affiliation:
Department of Mechanical Engineering, University of California, Riverside, 92521
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Abstract

This work describes the fabrication of highly sensitive graphene-based field effect transistor (FET) biosensors in a cost-effective way and its application in label-free DNA detection. CVD graphene was used to achieve mass production of FET device through photolithography method. Non-covalent functionalization of graphene with 1-Pyrenebutanoic acid succinimidyl ester ensures the high conductivity and sensitivity of the device. The present device could reach the low detection limit as low as 3*10-9 M.

Keywords

sensorchemical vapor deposition (CVD) (chemical reaction)electronic material

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References

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