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Micromechanics-Based Modeling of Biological Tissues Using the High-Fidelity Generalized Method of Cells

Published online by Cambridge University Press:  01 February 2011

Marek-Jerzy Pindera
Marek-Jerzy Pindera*
Affiliation:
Civil Engineering Department, University of Virginia Charlottesville, Virginia 22904–4742
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Abstract

The fundamental problem of micromechanics is the prediction of overall response of a composite material given the properties or response of the individual constituents and their internal geometric arrangement. The recently developed High-Fidelity Generalized Method of Cells is a promising micromechanics model whose predictive capability has been demonstrated for infinitesimal deformations in the presence of inelastic constituent behavior. The extension of this micromechanics model to the finite-deformation regime and incorporation of the quasi-linear viscoelasticity theory for the constituent response extends the range of this model's applicability to the bio-engineering area. Herein, an application involving the response of mitral valve chordae tendineae is presented that demonstrates the model's capability to mimic experimentally-observed response of this class of biological tissues rooted in their characteristic microstructures.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 844: Symposium Y – Mechanical Properties of Bio-Inspired and Biological Materials , 2004 , Y4.5
Copyright
Copyright © Materials Research Society 2005

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References

REFERENCES

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