Skip to main content
×
×
Home

Self-Assembled Lipid Tubules: Synthesis, Characterization, and Ordered Arrays

  • Yue Zhao (a1), Nidhi Mahajan (a2) and Jiyu Fang (a3)
Abstract

The rolling of lipid bilayer sheets into hollow cylindrical tubules have emerged as a group of interesting supramolecular nanostructures. Here, we image the self-assembled tubules of 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphochloline (DC8,9PC) with atomic force microscopy. Nanoscale ripple structures with a periodicity of ~ 200nm in the cylindrical lipid tubules are observed. We develop two simple methods based on microfluidic networks and surface patterning to produce two dimensional ordered arrays of parallel aligned lipid tubules on substrates.

Copyright
References
Hide All
1.Schnur, J. M., Science. 262, 1669(1993).
2.Shimizu, T., Masuda, M., Minamikawa, H., Chem, Rev. 105, 1401(2005).
3.Yager, P., Schoen, P. E., Mol. Cryst. Liq. Cryst. 106, 371(1984).
4.Thomas, B. N., Corcoran, R. C., Cotant, C. L., Lindemann, C. M., Kirsch, J. E., Persichini, P. J., J. Am. Chem. Soc. 120, 12178(1998).
5.Song, J., Cheng, Q., Kopta, S., Stevens, R. C., J. Am. Chem. Soc. 123, 3205(2001).
6.John, G., Masuda, M., Okada, Y., Yase, K., Shimizu, T., Adv. Mater. 13, 715(2001).
7.Lee, S. B., Koepsel, R., Stolz, D. B., Warriner, H. B., Russell, A. J., J. Am. Chem. Soc. 126, 13400(2004).
8.Seddon, A. M., Patel, H. M., Burkett, S. L., Mann, S., Angew. Chem. Int. Ed. 41, 2988(2002).
9.Price, R. R., Dressick, W. J., Singh, A., J. Am. Chem. Soc. 125, 11259(2003).
10.Yang, B., Kamiya, S., Shimizu, Y., Koshizaki, N., Shimizu, T, Chem. Mater. 16, 2826(2004).
11.Zhao, Y., Mahajan, N., Fang, J. Y., Small. 2, 364 (2006).
12.Wilson-Kubalek, E. M., Brown, R. E., Celia, H., Milligan, R. A., Proc. Natl. Acad. Sci. USA. 95, 8040(1998).
13.Melia, T. J., Sowa, M. E., Schutze, L., Wensel, T. G., J. Struct. Biol. 128, 119(1999).
14.Schnur, J. M., Price, R. R., Rudolph, A. S., J. Control. Release. 28, 3(1994).
15.Meilander, N. J., Pasumarthy, M. K., Kowalczyk, T. H., Cooper, M. J., Bellamkonda, R. V., J. Control. Release. 88, 321(2003).
16.Mahajan, N., Zhao, Y., Du, T., Fang, J. Y., Langmuir, 22, 1973(2006).
17.Mahajan, N., Fang, J. Y., Langmuir, 21, 3153(2005).
18.Zhao, Y., Fang, J. Y., Langmuir, 22, 1891(2006).
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

MRS Online Proceedings Library (OPL)
  • ISSN: -
  • EISSN: 1946-4274
  • URL: /core/journals/mrs-online-proceedings-library-archive
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed