Hostname: page-component-848d4c4894-wzw2p Total loading time: 0 Render date: 2024-05-03T18:22:34.542Z Has data issue: false hasContentIssue false

Sterilization Mode Effect on the Hydration Rate of Calcium Sulfate Hemihydrate

Published online by Cambridge University Press:  15 February 2011

T. R. Devine*
Affiliation:
USG Corporation, 700 N. Highway 45, Libertyville, Illinois 60048
Get access

Abstract

Plaster bandages have been found to support bacteria. The sterilization of plaster (calcium sulfate hemihydrate) for use as an implant biomaterial is, therefore, a primary concern. Heat sterilization can significantly alter material properties and the kinetics of plaster hydration. A study has been done of the effects of sterilization by gamma radiation and by ethylene oxide on the hydration rate of plaster. Three hemihydrate bases with differing water requirements and hydration rates were sterilized by each method. Adiabatic temperature rise was used to follow hydration. Five outcomes were measured and analyzed. These outcomes include the induction period, maximum rate of temperature rise (MRR), time to MRR, total temperature rise, and time to maximum temperature. Neither sterilization mode was found to significantly alter the hydration process of any of the plaster bases. From a material property standpoint, either gamma radiation or ethylene oxide treatment is preferred to heat sterization of calcium sulfate hemihydrate.

Type
Research Article
Copyright
Copyright © Materials Research Society 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Elkins, A. D. and Jones, Larry P., “The Effects of Plaster of Paris and Autogenous Cancellous Bone on the Healing of Cortical Defects in the Femurs of Dogs,” Veterina Surgery. 17, 2, 7176, 1988.Google Scholar
2. Gibbons, R. J. and Ewing, J. B., “Sterilization of Plaster of Paris Bandages,” Canadian Medical Association Journal, 60 618620, 1949.Google Scholar
3. Frame, John W. and Combe, Edward C., “The Effects of Sterilization on the Properties of Calcium Sulphate Hemihydrate,” Journal of Applied Chemistry and Biotechnology, 3, 493500, 1973.Google Scholar
4. Cowden, K., Giammara, B., Devine, T. and Hanker, J., “Effects of Sterilization Modes on the Mechanical Strengths of Plaster of Paris Implants,” p. 690, Proceedings ogfft 47th Annual Meeting of the Electron Microscopy Society f America, ed. Bailey, G. W., San Francisco Press, Inc., 1989.Google Scholar
5. Peltier, Leonard F., “The Use of Plaster of Paris to Fill Defects in Bone,” Clinical Orthopaedics, 21 131, 1961.Google Scholar
6. McKee, J. Cooper and Bailey, Byron J., “Calcium Sulfate as a Mandibular Implant,” Otolaryngolov and Head and Neck Surgery;92(3), 227286, 1984.Google Scholar
7. Mackey, Desmond, Varlet, Alain, and Debeaumont, Daniel, “Antibiotic Loaded Plaster of Paris Pellets: An jn Vitro Study of a Possible Method of Local Antibiotic Therapy in Bone Infection,” Clinical Orthopaedics and Related Research. 167, 263268, 1982.Google Scholar
8. Frame, J. W., “Porous Calcium Sulphate Dihydrate as a Biodegradable Implant in Bone,” Journal oqf Dentistr, 3(4), 177187, 1974.Google Scholar
9. Murray, E. G. D. and Denton, G. D., “Plaster of Paris as a Source of Infection in Tetanus and Gas-gangrene,” Canadian Medica Association Journal 60, 14, 1949.Google Scholar
10. Greenberg, L., “A Bacteriological Analysis of Plaster of Paris Bandages,” Canadian Medical Association Journal, 60, 47, 1949.Google Scholar