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Titanium Nanosurface Modification by Anodization for Orthopedic Applications

Published online by Cambridge University Press:  01 February 2011

Chang Yao ,
Elliott B. Slamovich  and
Thomas J. Webster
Chang Yao
Affiliation:
School of Materials Engineering, Purdue University, West Lafayette, IN 47907
Elliott B. Slamovich
Affiliation:
School of Materials Engineering, Purdue University, West Lafayette, IN 47907
Thomas J. Webster
Affiliation:
School of Materials Engineering, Purdue University, West Lafayette, IN 47907 Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907
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Abstract

Titanium is broadly used in orthopedic and dental applications mainly because of its optimal mechanical properties in load-bearing applications. However, insufficient new bone formation is frequently observed on titanium which sometimes leads to implant loosening and failure. For this reason, the objective of the present in vitro study was to modify the surface of conventional titanium to include nanostructured surface features that promote the functions of osteoblasts (bone-forming cells). This study focused on creating nanostructured titanium surfaces since bone itself has a large degree of nanostructured roughness that bone cells are accustomed to interacting with. In this study, the surface of titanium was modified by anodic oxidation techniques. The electrolyte used for anodization was hydrofluoric acid. Depending on acid concentration and anodization time, two kinds of different nano-architectures, either particulate or tube-like structures, were formed on the titanium surface. X-ray diffraction results confirmed that the titanium oxide formed on the surface of titanium was amorphous. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) were used to characterize the surface morphology. Cell adhesion studies showed that the anodized nanostructured titanium surface promoted osteoblast adhesion compared to non-anodized titanium. This result indicated that anodization may be a simple method to modify the surface of titanium implants to enhance bone-forming cell function thereby increasing orthopedic implant efficacy.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 845: Symposium AA – Nanoscale Materials Science in Biology and Medicine , 2004 , AA9.11
Copyright
Copyright © Materials Research Society 2005

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References

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