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X-ray powder diffraction data for deferasirox, C21H15N3O4

Published online by Cambridge University Press:  19 September 2016

Qiaohong Du ,
Qing Wang ,
Xinnuo Xiong ,
Xia Zeng  and
Hui Li
Qiaohong Du
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Qing Wang
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Xinnuo Xiong
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Xia Zeng
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Hui Li*
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
*
a) Author to whom correspondence should be addressed. Electronic mail: lihuilab@sina.com
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Abstract

X-ray powder diffraction data, unit-cell parameters, and space group for deferasirox, C21H15N3O4, are reported [a = 8.821(7) Å, b = 26.798(2) Å, c = 7.540(4) Å, α = 90°, β = 94.655(2)°, γ = 90°, unit-cell volume V = 1776.7(3) Å3, Z = 4, ρ cal = 1.396 g cm−3, and space group P21/c]. All measured lines were indexed and are consistent with the P21/c space group. No detectable impurity was observed.

Keywords

X-ray powder diffractiondeferasirox

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Type
Data Reports
Information
Powder Diffraction , Volume 31 , Issue 4 , December 2016 , pp. 298 - 300
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Copyright
Copyright © International Centre for Diffraction Data 2016 

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References

Boultif, A. and Louër, D. (1991). “Indexing of powder diffraction patterns for low-symmetry lattices by the successive dichotomy method,” J. Appl. Crystallogr. 24, 987–993.CrossRefGoogle Scholar
de Wolff, P. M. (1968). “A simplified criterion for the reliability of a powder pattern indexing,” J. Appl. Crystallogr. 1, 108–113.Google Scholar
Neufeld, E. J. (2006). “Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions,” Blood 107(9), 3436–3441.Google Scholar
Pawley, G. S. (1981). “Unit-cell refinement from powder diffraction scans,” J. Appl. Crystallogr. 14(6), 357–361.CrossRefGoogle Scholar
Reed, C., Ibrahim, A., Edwards, J. E., Walot, I., and Spellberg, B. (2006). “Deferasirox, an iron-chelating agent, as salvage therapy for rhinocerebral mucormycosis,” Antimicrob. Agents Chemother. 50(11), 3968–3969.CrossRefGoogle ScholarPubMed
Smith, G. S. and Snyder, R. L. (1979). “FN: a criterion for rating powder diffraction patterns and evaluating the reliability of powder indexing,” J. Appl. Crystallogr. 12, 60–65.Google Scholar
Steinhauser, S., Heinz, U., Bartholomä, M., Weyhermüller, T., Nick, H., and Hegetschweiler, K. (2004). “Complex formation of ICL670 and related ligands with FeIII and FeII,” Eur. J. Inorg. Chem. 2004(21), 4177–4192.CrossRefGoogle Scholar
Wang, Q., Sun, Q. M., Li, S. S., Guo, L. Q., and Li, H. (2016). “X-ray powder diffraction data for drospirenone, C24H30O3 ,” Powder Diffr. 31(1), 63–65.Google Scholar
Xu, K. L., Liang, B., Wu, X. Q., Zhang, L. L., Tang, P. X., and Li, H. (2014). “X-ray powder diffraction data for levetiracetam,” Powder Diffr. 29(1), 51–52.Google Scholar
Yang, L. P., Keam, S. J., and Keating, G. M. (2007). “A review of its use in the management of transfusional chronic iron overload,” Drugs 67(15), 2211–2230.Google Scholar
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