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Anticonvulsant monitoring in psychiatric practice

  • Debbie Nelson (a1) and Douglas Gray (a1)
Abstract
Aims and Method

A Medline literature search revealed a large number of articles on anticonvulsant monitoring. More relevant articles were selected with the aim of summarising current best practice in this area.

Results

Most articles were written to address monitoring in epilepsy and not psychiatric illness. Serum ranges should only be regarded as guidelines. Some patients may show toxic signs at therapeutic serum levels while others may show tolerance and require higher levels.

Clinical Implications

Appropriate monitoring of serum levels improves efficacy and enhances safety. Clinician ignorance may lead to inappropriate or inaccurate sampling with resultant adverse consequences for the patient.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
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Bazire, S. (1999) Psychotropic Drug Directory. Wiltshire: Quay Books Division.
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Chadwick, D. (1987) Overuse of monitoring of blood concentrations of antiepileptic drugs (Letter). BMJ, 294, 723724.
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BJPsych Bulletin
  • ISSN: 0955-6036
  • EISSN: 1472-1473
  • URL: /core/journals/bjpsych-bulletin
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Anticonvulsant monitoring in psychiatric practice

  • Debbie Nelson (a1) and Douglas Gray (a1)
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