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Investigation of depot neuroleptic injection site reactions

  • Julie C. Jones (a1), Jennifer C. Day (a2), John R. Taylor (a3) and Christopher S. Thomas (a4)
Abstract
Aims and method

A cross-sectional survey was performed on 318 patients receiving depot medication. The presence or absence of a depot site reaction was recorded by psychiatric nursing staff on a standardised form.

Results

Seventeen per cent of patients were found to have clinically significant depot site reactions. Such reactions were associated with increased frequency of injection and increased total volume of depot administered in the previous 12 months. The severity of a depot site reaction was unrelated to the concentration of depot preparation administered.

Clinical implications

Depot site reactions may be reduced by maximising the interval between injections and using low volume (highly concentrated) preparations of depot neuroleptic medication.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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References
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BJPsych Bulletin
  • ISSN: 0955-6036
  • EISSN: 1472-1473
  • URL: /core/journals/bjpsych-bulletin
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Investigation of depot neuroleptic injection site reactions

  • Julie C. Jones (a1), Jennifer C. Day (a2), John R. Taylor (a3) and Christopher S. Thomas (a4)
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