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Commentary: Recent disputes on the role of serotonin in depression

Published online by Cambridge University Press:  12 September 2023

Nikolas Rose*
Affiliation:
Research School of Social Sciences and School of Sociology, Australian National University, Canberra, Australia Institute of Advanced Studies, University College London, London, UK
*
Corresponding Author Nikolas Rose Email: ucqhnr0@ucl.ac.uk

Abstract

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Type
Commentary
Copyright
Copyright © The Author(s), 2023. Published by Cambridge University Press

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References

Belujon, P., & Grace, A. A. (2017). Dopamine system dysregulation in major depressive disorders. International Journal of Neuropsychopharmacology, 20(12), 10361046.CrossRefGoogle ScholarPubMed
Carlson, P. J., Singh, J. B., Zarate, C. A. Jr, Drevets, W. C., & Manji, H. K. (2006). Neural circuitry and neuroplasticity in mood disorders: Insights for novel therapeutic targets. NeuroRx, 3(1), 2241.CrossRefGoogle ScholarPubMed
Charnay, Y., & Léger, L. (2022). Brain serotonergic circuitries. Dialogues in Clinical Neuroscience, 12(4), 471487.CrossRefGoogle Scholar
Goldberg, D. (2011). The heterogeneity of “major depression”. World Psychiatry, 10(3), 226228.CrossRefGoogle ScholarPubMed
Hacking, I. (1995). The looping effects of human kinds. In Sperber, D., Premack, D., & Premack, A. J. (Eds.), Causal cognition: A multi-disciplinary approach (pp. 351383). Oxford: Clarendon Press.Google Scholar
Jauhar, S., Arnone, D., Baldwin, D. S., Bloomfield, M., Browning, M., Cleare, A. J., … Fu, C. (2023). A leaky umbrella has little value: Evidence clearly indicates the serotonin system is implicated in depression. Molecular Psychiatry, 2023, 14.Google Scholar
Jesulola, E., Micalos, P., & Baguley, I. J. (2018). Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model-are we there yet? Behavioural Brain Research, 341, 7990.CrossRefGoogle Scholar
Liu, B., Liu, J., Wang, M., Zhang, Y., & Li, L. (2017). From serotonin to neuroplasticity: Evolvement of theories for major depressive disorder. Frontiers in Cellular Neuroscience, 11, 305.CrossRefGoogle ScholarPubMed
Maletic, V., Eramo, A., Gwin, K., Offord, S. J., & Duffy, R. A. (2017). The role of norepinephrine and its α-adrenergic receptors in the pathophysiology and treatment of major depressive disorder and schizophrenia: A systematic review. Frontiers in Psychiatry, 8, 42.CrossRefGoogle ScholarPubMed
Massabki, I., & Abi-Jaoude, E. (2021). Selective serotonin reuptake inhibitor ‘discontinuation syndrome’ or withdrawal. The British Journal of Psychiatry, 218(3), 168171. doi:10.1192/bjp.2019.269.CrossRefGoogle ScholarPubMed
Moncrieff, J., Cooper, R. E., Stockmann, T., Amendola, S., Hengartner, M. P., & Horowitz, M. A. (2022). The serotonin theory of depression: A systematic umbrella review of the evidence. Molecular Psychiatry, 2022, 114.Google Scholar
Moriguchi, S., Takamiya, A., Noda, Y., Horita, N., Wada, M., Tsugawa, S., … ElSalhy, M. (2019). Glutamatergic neurometabolite levels in major depressive disorder: A systematic review and meta-analysis of proton magnetic resonance spectroscopy studies. Molecular Psychiatry, 24(7), 952964.CrossRefGoogle ScholarPubMed
Murray, R. M., Quattrone, D., Natesan, S., van Os, J., Nordentoft, M., Howes, O., … Taylor, D. (2016). Should psychiatrists be more cautious about the long-term prophylactic use of antipsychotics? The British Journal of Psychiatry, 209(5), 361365.CrossRefGoogle ScholarPubMed
Schildkraut, J. J. (1965). The catecholamine hypothesis of affective disorders: A review of supporting evidence. American Journal of Psychiatry, 122, 509522.CrossRefGoogle ScholarPubMed