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Psychological Medicine Psychological Medicine

Article contents

Work stress precipitates depression and anxiety in young, working women and men

Published online by Cambridge University Press:  04 April 2007

MARIA MELCHIOR ,
AVSHALOM CASPI ,
BARRY J. MILNE ,
ANDREA DANESE ,
RICHIE POULTON  and
TERRIE E. MOFFITT
MARIA MELCHIOR
Affiliation:
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, London, UK Department of Psychology, University of Wisconsin, Madison, WI, USA INSERM U687-IFR69, Saint-Maurice, France
AVSHALOM CASPI
Affiliation:
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, London, UK Department of Psychology, University of Wisconsin, Madison, WI, USA
BARRY J. MILNE
Affiliation:
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, London, UK
ANDREA DANESE
Affiliation:
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, London, UK
RICHIE POULTON
Affiliation:
Dunedin School of Medicine, University of Otago, New Zealand
TERRIE E. MOFFITT*
Affiliation:
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, London, UK Department of Psychology, University of Wisconsin, Madison, WI, USA
*
*Address for correspondence: Professor Terrie Moffitt, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK. (Email: t.moffitt@iop.kcl.ac.uk)
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Abstract

Background

Rates of depression have been rising, as have rates of work stress. We tested the influence of work stress on diagnosed depression and anxiety in young working adults.

Method

Participants were enrolled in the Dunedin study, a 1972–1973 longitudinal birth cohort assessed most recently in 2004–2005, at age 32 (n=972, 96% of 1015 cohort members still alive). Work stress (psychological job demands, work decision latitude, low work social support, physical work demands) was ascertained by interview. Major depressive disorder (MDD) and generalized anxiety disorder (GAD) were ascertained using the Diagnostic Interview Schedule (DIS) and diagnosed according to DSM-IV criteria.

Results

Participants exposed to high psychological job demands (excessive workload, extreme time pressures) had a twofold risk of MDD or GAD compared to those with low job demands. Relative risks (RRs) adjusting for all work characteristics were: 1·90 [95% confidence interval (CI) 1·22–2·98] in women, and 2·00 (95% CI 1·13–3·56) in men. Analyses ruled out the possibility that the association between work stress and disorder resulted from study members' socio-economic position, a personality tendency to report negatively, or a history of psychiatric disorder prior to labour-market entry. Prospective longitudinal analyses showed that high-demand jobs were associated with the onset of new depression and anxiety disorder in individuals without any pre-job history of diagnosis or treatment for either disorder.

Conclusions

Work stress appears to precipitate diagnosable depression and anxiety in previously healthy young workers. Helping workers cope with work stress or reducing work stress levels could prevent the occurrence of clinically significant depression and anxiety.

Type
Original Article
Information
Psychological Medicine , Volume 37 , Issue 8 , August 2007 , pp. 1119 - 1129
Copyright
Copyright © Cambridge University Press 2007

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References

Abramson, L. Y., Seligman, M. E. & Teasdale, J. D. (1978). Learned helplessness in humans: critique and reformulation. Journal of Abnormal Psychology 87, 49–74.CrossRefGoogle ScholarPubMed
APA (1980). Diagnostic and Statistical Manual of Mental Disorders (3rd edn). American Psychiatric Association: Washington, DC.Google Scholar
APA (1987). Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised). American Psychiatric Association: Washington, DC.Google Scholar
APA (1994). Diagnostic and Statistical Manual of Mental Disorders (4th edn). American Psychiatric Association: Washington, DC.Google Scholar
Avitsur, R., Stark, J. L. & Sheridan, J. F. (2001). Social stress induces glucocorticoid resistance in subordinate animals. Hormones and Behavior 39, 247–257.CrossRefGoogle ScholarPubMed
Barros, A. J. & Hirakata, V. N. (2003). Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. BMC Medical Research Methodology 3, 1–13.CrossRefGoogle ScholarPubMed
Beck, A. T., Rush, A. J., Shaw, B. F. & Emery, G. (1979). Cognitive Therapy of Depression. Guilford Press: New York.Google Scholar
Belli, R. F., Shay, W. L. & Stafford, F. P. (2001). Event history calendars and question list surveys: a direct comparison of interviewing methods. Public Opinion Quarterly 65, 45–74.CrossRefGoogle ScholarPubMed
Berkman, L. F. & Glass, T. (2000). Social integration, social networks, social support and health. In Social Epidemiology (ed. Berkman, L. F. and Kawachi, I.), pp. 137–173. Oxford University Press: New York.Google Scholar
Bromet, E. J., Dew, M. A., Parkinson, D. K., Cohen, S. & Schwartz, J. E. (1992). Effects of occupational stress on the physical and psychological health of women in a microelectronics plant. Social Science and Medicine 34, 1377–1383.CrossRefGoogle Scholar
Bromet, E. J., Dew, M. A., Parkinson, D. K. & Schulberg, H. C. (1988). Predictive effects of occupational and marital stress on the mental health of a male workforce. Journal of Organizational Behavior 9, 1–13.CrossRefGoogle Scholar
Caspi, A., Moffitt, T. E., Thorton, A., Freedman, D., Amell, J. W., Harrington, H. L., Smeijers, J. & Silva, P. A. (1996). The Life History Calendar: a research and clinical assessment method for collecting retrospective event-history data. International Journal of Methods in Psychiatric Research 6, 101–114.3.3.CO;2-E>CrossRefGoogle Scholar
Costello, A., Edelbrock, C., Kalas, R., Kessler, M. & Klaric, S. A. (1982). Diagnostic Interview Scheduled for Children (DISC). National Institute of Mental Health: Rockville, MD.Google Scholar
Cropley, M., Steptoe, A. & Joekes, K. (1999). Job strain and psychiatric morbidity. Psychological Medicine 29, 1411–1416.CrossRefGoogle ScholarPubMed
Davis, P., Jenkin, G. & Coope, P. (2003). New Zealand Socio-economic Index 1996. Statistics New Zealand: Wellington, New Zealand.Google Scholar
de Kloet, E. R., Joëls, M. & Holsboer, F. (2005). Stress and the brain: from adaptation to disease. Nature Reviews Neuroscience 6, 463–475.CrossRefGoogle ScholarPubMed
Eurofound (2005). Fourth European Working Conditions Survey. European Foundation for the Improvement of Living and Working Conditions. Available online at: www.eurofound.eu.int/pubdocs/2006/78/en/1/ef0678en.pdf (accessed 13 December 2006).Google Scholar
Hanley, J. (2001). A heuristic approach to the formulas for population attributable fraction. Journal of Epidemiology and Community Health 55, 508–514.CrossRefGoogle ScholarPubMed
John, O. & Srivastata, S. (1999). The Big Five taxonomy: history, measurement, and theoretical perspectives. In Handbook of Personality (ed. Pervin, L. and John, O.), pp. 102–138. Guilford Press: New York.Google Scholar
Johnson, J., Hall, E. & Theorell, T. (1989). Combined effects of job strain and social isolation on cardiovascular disease morbidity and mortality in a random sample of the Swedish male working population. Scandinavian Journal of Work and Environmental Health 15, 271–279.CrossRefGoogle Scholar
Karasek, R. & Theorell, T. (1990). Healthy Work: Stress, Productivity and the Reconstruction of Working Life. Basic Books: New York.Google Scholar
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R. & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry 62, 593–602.CrossRefGoogle ScholarPubMed
Kessler, R. C., McGonagle, K. A., Nelson, C. B., Hughes, M., Swartz, M. & Blazer, D. G. (1994). Sex and depression in the National Comorbidity Survey. II. Cohort effects. Journal of Affective Disorders 30, 15–26.CrossRefGoogle ScholarPubMed
Kim-Cohen, J., Caspi, A., Moffitt, T. E., Harrington, H., Milne, B. J. & Poulton, R. (2003). Prior juvenile diagnoses in adults with mental disorder: developmental follow-back of a prospective longitudinal cohort. Archives of General Psychiatry 60, 709–711.CrossRefGoogle ScholarPubMed
Krueger, R. F., Caspi, A., Moffitt, T. E. & Silva, P. A. (1998). The structure and stability of common mental disorders (DSM III-R): a longitudinal-epidemiological study. Journal of Abnormal Psychology 107, 216–227.CrossRefGoogle ScholarPubMed
Mausner-Dorsch, H. & Eaton, W. W. (2000). Psychosocial work environment and depression: epidemiologic assessment of the demand-control model. American Journal of Public Health 90, 1765–1770.Google ScholarPubMed
McEwen, B. S. (1998). Protective and damaging effects of stress mediators: allostatis and allostatic load. New England Journal of Medicine 338, 171–179.CrossRefGoogle Scholar
Melin, B., Lundberg, U., Soderlund, J. & Granqvist, M. (1999). Psychological and physiological stress reactions of male and female assembly workers: a comparison between two different forms of work organization. Journal of Organizational Behavior 20, 47–61.3.0.CO;2-F>CrossRefGoogle Scholar
Mineka, S., Watson, D. & Clark, L. A. (1998). Comorbidity of anxiety and unipolar mood disorders. Annual Review of Psychology 49, 377–412.CrossRefGoogle ScholarPubMed
Mino, Y., Babazono, A., Tsuda, T. & Yasuda, N. (2006). Can stress management at the workplace prevent depression? A randomized controlled trial. Psychotherapy and Psychosomatics 75, 177–182.CrossRefGoogle ScholarPubMed
Moffitt, T. E., Caspi, A., Harrington, H., Milne, B. J., Melchior, M., Goldberg, D. & Poulton, R. (2007). Generalized anxiety disorder and depression: childhood risk factors in a birth cohort followed to age 32. Psychological Medicine 37, 441–452.CrossRefGoogle Scholar
Moffitt, T. E., Caspi, A., Rutter, M. & Silva, P. A. (2001). Sex Differences in Antisocial Behaviour: Conduct Disorder, Delinquency, and Violence in the Dunedin Longitudinal Study. Cambridge University Press: Cambridge, UK.CrossRefGoogle Scholar
Niedhammer, I., Goldberg, M., Leclerc, A., Bugel, I. & David, S. (1998). Psychosocial factors at work and subsequent depressive symptoms in the Gazel cohort. Scandinavian Journal of Work, Environment and Health 24, 197–205.CrossRefGoogle ScholarPubMed
NIOSH (1999). Stress at Work. National Institute of Occupational Health and Safety (www.cdc.gov/niosh/stresswk.html). Accessed 13 December 2006.Google Scholar
OECD (2006). OECD Factbook: Economic, Environmental and Social Statistics. Organisation for Economic Co-operation and Development (www.oecd.org/). Accessed 13 December 2006.Google Scholar
Pariante, C. M. & Miller, A. H. (2001). Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biological Psychiatry 49, 391–404.CrossRefGoogle ScholarPubMed
Parkes, K. R. (1990). Coping, negative affectivity, and the work environment: additive and interactive predictors of mental health. Journal of Applied Psychology 75, 399–409.CrossRefGoogle ScholarPubMed
Paterniti, S., Niedhammer, I., Lang, T. & Consoli, S. M. (2002). Psychosocial factors at work, personality traits and depressive symptoms. Longitudinal results from the GAZEL Study. British Journal of Psychiatry 181, 111–117.CrossRefGoogle ScholarPubMed
Phelan, J., Schwartz, J. E., Bromet, E. J., Dew, M. A., Parkinson, D. K., Schulberg, H. C., Dunn, L. O., Blane, H. & Curtis, E. C. (1991). Work stress, family stress and depression in professional and managerial employees. Psychological Medicine 21, 999–1012.CrossRefGoogle ScholarPubMed
Robins, L., Cottler, L., Bucholz, K. & Compton, W. (1995). Diagnostic Interview Schedule for DSM-IV. Washington University School of Medicine: St Louis, MO.Google Scholar
Robins, L., Helzer, J., Cottler, L. & Goldring, E. (1989). Diagnostic Interview Schedule, Version III-R. Washington University School of Medicine: St Louis, MO.Google Scholar
Sapolsky, R. M., Krey, L. C. & McEwen, B. S. (1986). The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocrine Reviews 7, 284–301.CrossRefGoogle ScholarPubMed
Schwarzer, R. (1998). Stress and coping from a social-cognitive perspective. Annals of the New York Academy of Sciences 30, 531–537.CrossRefGoogle Scholar
Shields, M. (1999). Long working hours and health. Health Reports 11, 33–48.Google ScholarPubMed
Stansfeld, S. A., Fuhrer, R., Head, J., Ferrie, J. & Shipley, M. (1997). Work and psychiatric disorder in the Whitehall II Study. Journal of Psychosomatic Research 43, 73–81.CrossRefGoogle ScholarPubMed
Stansfeld, S. A., Fuhrer, R., Shipley, M. & Marmot, M. G. (1999). Work characteristics predict psychiatric disorder: prospective results from the Whitehall II study. Occupational and Environmental Medicine 56, 302–307.CrossRefGoogle ScholarPubMed
Statistics New Zealand (1999). New Zealand Standard Classification of Occupations. Statistics New Zealand: Wellington, New Zealand.Google Scholar
Tennant, C. (2001). Work-related stress and depressive disorders. Journal of Psychosomatic Research 51, 697–704.CrossRefGoogle ScholarPubMed
Twenge, J. M. (2000). The age of anxiety? Birth cohort changes in anxiety and neuroticism, 1952–1993. Journal of Personality and Social Psychology 79, 1007–1021.CrossRefGoogle Scholar
Wang, P. S., Beck, A. L., Berglund, P., McKenas, D. K., Pronk, N. P., Simon, G. E. & Kessler, R. C. (2004). Effects of major depression on moment-in-time work performance. American Journal of Psychiatry 161, 1885–1891.CrossRefGoogle ScholarPubMed
WHO (2001). World Health Report 2001 – Mental Health: New Understanding, New Hope. World Health Organization: Geneva (www.who.int/whr/2001/en/). Accessed 13 December 2006.Google Scholar
307
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