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Associations between diurnal preference, sleep quality and externalizing behaviours: a behavioural genetic analysis

  • N. L. Barclay (a1), T. C. Eley (a2), B. Maughan (a2), R. Rowe (a3) and A. M. Gregory (a1)...

Certain aspects of sleep co-occur with externalizing behaviours in youth, yet little is known about these associations in adults. The present study: (1) examines the associations between diurnal preference (morningness versus eveningness), sleep quality and externalizing behaviours; (2) explores the extent to which genetic and environmental influences are shared between or are unique to these phenotypes; (3) examines the extent to which genetic and environmental influences account for these associations.


Questionnaires assessing diurnal preference, sleep quality and externalizing behaviours were completed by 1556 young adult twins and siblings.


A preference for eveningness and poor sleep quality were associated with greater externalizing symptoms [r=0.28 (95% CI 0.23–0.33) and 0.34 (95% CI 0.28–0.39), respectively]. A total of 18% of the genetic influences on externalizing behaviours were shared with diurnal preference and sleep quality and an additional 14% were shared with sleep quality alone. Non-shared environmental influences common to the phenotypes were small (2%). The association between diurnal preference and externalizing behaviours was mostly explained by genetic influences [additive genetic influence (A)=80% (95% CI 0.56–1.01)], as was the association between sleep quality and externalizing behaviours [A=81% (95% CI 0.62–0.99)]. Non-shared environmental (E) influences accounted for the remaining variance for both associations [E=20% (95% CI −0.01 to 0.44) and 19% (95% CI 0.01–0.38), respectively].


A preference for eveningness and poor sleep quality are moderately associated with externalizing behaviours in young adults. There is a moderate amount of shared genetic influences between the phenotypes and genetic influences account for a large proportion of the association between sleep and externalizing behaviours. Further research could focus on identifying specific genetic polymorphisms common to both sleep and externalizing behaviours.

Corresponding author
*Address for correspondence: Mrs N. L. Barclay, Department of Psychology, Goldsmiths, University of London, Lewisham Way, New Cross, London SE14 6NW, UK. (Email:
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Achenbach, TM (1991). Manual for the Youth Self-Report and 1991 Profile. University of Vermont Department of Psychiatry: Burlington, VT.
Achenbach, TM, Rescorla, LA (2003). Manual for the ASEBA Adult Forms & Profiles. University of Vermont, Research Center for Children, Youth and Families: Burlington, VT.
Alia-Klein, N, Goldstein, RZ, Kriplani, A, Logan, J, Tomasi, D, Williams, B, Telang, F, Shumay, E, Biegon, A, Craig, IW, Henn, F, Wang, GJ, Volkow, ND, Fowler, JS (2008). Brain monoamine oxidase A activity predicts trait aggression. Journal of Neuroscience 28, 50995104.
Anderson, MJ, Petros, TV, Beckwith, BE, Mitchell, WW, Fritz, S (1991). Individual differences in the effect of time of day on long-term memory access. American Journal of Psychology 104, 241255.
Aronen, ET, Paavonen, EJ, Fjallberg, M, Soininen, M, Torronen, J (2000). Sleep and psychiatric symptoms in school-age children. Journal of the American Academy of Child and Adolescent Psychiatry 39, 502508.
Backhaus, J, Junghanns, K, Broocks, A, Riemann, D, Hohagen, F (2002). Test-retest reliability and validity of the Pittsburgh Sleep Quality Index in primary insomnia. Journal of Psychosomatic Research 53, 737740.
Barclay, NL, Eley, TC, Buysse, DJ, Archer, SN, Gregory, AM (2010). Diurnal preference and sleep quality: same genes? A study of young adult twins. Chronobiology International 27, 278296.
Brummett, BH, Krystal, AD, Ashley-Koch, A, Kuhn, CM, Zuchner, S, Siegler, IC, Barefoot, JC, Ballard, EL, Gwyther, LP, Williams, RB (2007 a). Sleep quality varies as a function of 5-HTTLPR genotype and stress. Psychosomatic Medicine 69, 621624.
Brummett, BH, Krystal, AD, Siegler, IC, Kuhn, C, Surwit, RS, Zuchner, S, Ashley-Koch, A, Barefoot, JC, Williams, RB (2007 b). Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality. Psychosomatic Medicine 69, 396401.
Button, TMM, Lau, JYF, Maughan, B, Eley, TC (2008). Parental punitive discipline, negative life events and gene-environment interplay in the development of externalizing behavior. Psychological Medicine 38, 2939.
Buysse, DJ, Reynolds, CF, Monk, TH, Berman, SR, Kupfer, DJ (1989). The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Research 28, 192213.
Chelminski, I, Ferraro, FR, Pertros, T, Plaud, JJ (1997). Horne and Ostberg Questionnaire: a score distribution in a large sample of young adults. Personality and Individual Differences 23, 647652.
Cohen, DJ, Dibble, E, Grawe, JM, Pollin, W (1975). Reliably separating identical from fraternal twins. Archives of General Psychiatry 32, 13711375.
Dahl, RE, Pelham, WE, Wierson, M (1991). The role of sleep disturbances in attention-deficit disorder symptoms – a case-study. Journal of Pediatric Psychology 16, 229239.
Eley, TC (1997). General genes: A new theme in developmental psychopathology. Current Directions in Psychological Science 6, 9095.
Eley, TC, Liang, HL, Plomin, R, Sham, P, Sterne, A, Williamson, R, Purcell, S (2004). Parental familial vulnerability, family environment, and their interactions as predictors of depressive symptoms in adolescents. Journal of the American Academy of Child and Adolescent Psychiatry 43, 298306.
Ford, DE, Kamerow, DB (1989). Epidemiologic study of sleep disturbances and psychiatric disorders – an opportunity for prevention. Journal of the American Medical Association 262, 14791484.
Foshee, VA, Ennett, ST, Bauman, KE, Suchindran, C (2005). The association between family violence and adolescent dating violence onset does it vary by race, socioeconomic status, and family structure? Journal of Early Adolescence 25, 317344.
Giannotti, F, Cortesi, F, Sebastiani, T, Ottaviano, S (2002). Circadian preference, sleep and daytime behaviour in adolescence. Journal of Sleep Research 11, 191199.
Gregory, AM, Caspi, A, Moffitt, TE, Poulton, R (2006). Family conflict in childhood: a predictor of later insomnia. Sleep 29, 10631067.
Gregory, AM, Eley, TC, O'Connor, TG, Plomin, R (2004). Etiologies of associations between childhood sleep and behavioral problems in a large twin sample. Journal of the American Academy of Child and Adolescent Psychiatry 43, 744751.
Gregory, AM, O'Connor, TG (2002). Sleep problems in childhood: A longitudinal study of developmental change and association with behavioral problems. Journal of the American Academy of Child and Adolescent Psychiatry 41, 964971.
Gregory, AM, van der Ende, J, Willis, TA, Verhulst, FC (2008). Parent-reported sleep problems during development and self-reported anxiety/depression, attention problems, and aggressive behavior later in life. Archives of Pediatrics & Adolescent Medicine 162, 330335.
Hall, M, Buysse, DJ, Nofzinger, EA, Reynolds, CF, Thompson, W, Mazumdar, S, Monk, TH (2008). Financial strain is a significant correlate of sleep continuity disturbances in late-life. Biological Psychology 77, 217222.
Healey, ES, Kales, A, Monroe, LJ, Bixler, EO, Chamberlin, K, Soldatos, CR (1981). Onset of insomnia – role of life-stress events. Psychosomatic Medicine 43, 439451.
Heuer, H, Kohlisch, O, Klein, W (2005). The effects of total sleep deprivation on the generation of random sequences of key-presses, numbers and nouns. Quarterly Journal of Experimental Psychology. Section A: Human Experimental Psychology 58, 275307.
Horne, JA, Östberg, O (1976). A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. International Journal of Chronobiology 4, 97–110.
Ireland, JL, Culpin, V (2006). The relationship between sleeping problems and aggression, anger, and impulsivity in a population of juvenile and young offenders. Journal of Adolescent Health 38, 649655.
Killgore, WDS, Balkin, TJ, Wesensten, NJ (2006). Impaired decision-making following 49 hours of sleep deprivation. Journal of Sleep Research 15, 7–13.
Kudielka, BM, Federenko, IS, Hellhammer, DH, Wust, S (2006). Morningness and eveningness: the free cortisol rise after awakening in ‘early birds’ and ‘night owls’. Biological Psychology 72, 141146.
Lau, JYF, Rijsdijk, FV, Eley, TC (2006). I think, therefore I am: a twin study of attributional style in adolescents. Journal of Child Psychology and Psychiatry 47, 696703.
Lindberg, N, Tani, P, Appelberg, B, Stenberg, D, Naukkarinen, H, Rimon, R, Porkka-Heiskanen, T, Virkkunen, M (2003). Sleep among habitually violent offenders with antisocial personality disorder. Neuropsychobiology 47, 198205.
McBurnett, K, Lahey, BB, Rathouz, PJ, Loeber, R (2000). Low salivary cortisol and persistent aggression in boys referred for disruptive behavior. Archives of General Psychiatry 57, 3843.
McGue, M, Bouchard, TJ (1984). Adjustment of twin data for the effects of age and sex. Behavior Genetics 14, 325343.
Meltzer, H, Gatward, R, Goodman, R, Ford, T (2000). Mental Health of Children and Adolescents in Great Britain. The Stationery Office: London.
Mezick, EJ, Matthews, KA, Hall, M, Strollo, PJ, Buysse, DJ, Kamarck, TW, Owens, JF, Reis, SE (2008). Influence of race and socioeconomic status on sleep: Pittsburgh Sleep SCORE project. Psychosomatic Medicine 70, 410416.
Miczek, KA, Fish, EW, de Almeida, RMM, Faccidomo, S, Debold, JF (2004). Role of alcohol consumption in escalation to violence. Annals of the New York Academy of Sciences 1036, 278289.
Moffitt, TE, Brammer, GL, Caspi, A, Fawcett, JP, Raleigh, M, Yuwiler, A, Silva, P (1998). Whole blood serotonin relates to violence in an epidemiological study. Biological Psychiatry 43, 446457.
Monk, TH, Buysse, DJ, Potts, JM, DeGrazia, JM, Kupfer, DJ (2004). Morningness-eveningness and lifestyle regularity. Chronobiology International 21, 435443.
Neale, MC (1997). Mx: Statistical Modeling. 4th Department of Psychiatry: Richmond, VA.
Neale, MC, Heath, AC, Hewitt, JK, Eaves, LJ, Fulker, DW (1989). Fitting genetic models with LISREL: hypothesis testing. Behavior Genetics 19, 3749.
Pajer, K, Gardner, W, Rubin, RT, Perel, J, Neal, S (2001). Decreased cortisol levels in adolescent girls with conduct disorder. Archives of General Psychiatry 58, 297302.
Plomin, R, DeFries, JC, McClearn, GE, McGuffin, P (2008). Behavioral Genetics. Worth Publishers: New York.
Roth, T, Kramer, MD, Lutz, T (1976). The effects of sleep deprivation on mood. Psychiatry Journal of the University of Ottawa 1, 136139.
Semiz, UB, Algul, A, Basoglu, C, Ates, MA, Ebrinc, S, Cetin, M, Gunes, C, Gunay, H (2008). The relationship between subjective sleep quality and aggression in male subjects with antisocial personality disorder. Turk Psikiyatri Dergisi 19, 373381.
Sham, P, Sterne, A, Purcell, S, Cherny, SS, Webster, M, Rijsdijk, FV, Asherson, P, Ball, D, Craig, I, Eley, TC, Goldberg, D, Gray, J, Mann, A, Owen, M, Plomin, R (2000). GENESiS: creating a composite index of the vulnerability to anxiety and depression in a community-based sample of siblings. Twin Research 3, 316322.
Smith, CS, Reilly, C, Midkiff, K (1989). Evaluation of three circadian rhythm questionnaires with suggestions for an improved measure of morningness. Journal of Applied Physiology 74, 728738.
Susman, EJ, Dockray, S, Schiefelbein, VL, Herwehe, S, Heaton, JA, Dorn, LD (2007). Morningness/eveningness, morning-to-afternoon cortisol ratio, and antisocial behavior problems during puberty. Developmental Psychology 43, 811822.
Vahtera, J, Kivimaeki, M, Hublin, C, Korkeila, K, Suominen, S, Paunio, T, Koskenvuo, M (2007). Liability to anxiety and severe life events as predictors of new-onset sleep disturbances. Sleep 30, 15371546.
Wolfson, AR, Carskadon, MA (1998). Sleep schedules and daytime functioning in adolescents. Child Development 69, 875887.
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