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    Nava, Nicoletta Treccani, Giulia Alabsi, Abdelrahman Kaastrup Mueller, Heidi Elfving, Betina Popoli, Maurizio Wegener, Gregers and Nyengaard, Jens Randel 2015. Temporal Dynamics of Acute Stress-Induced Dendritic Remodeling in Medial Prefrontal Cortex and the Protective Effect of Desipramine. Cerebral Cortex, p. bhv254.

    Torres, Ulysses S Portela-Oliveira, Eduardo Borgwardt, Stefan and Busatto, Geraldo F 2013. Structural brain changes associated with antipsychotic treatment in schizophrenia as revealed by voxel-based morphometric MRI: an activation likelihood estimation meta-analysis. BMC Psychiatry, Vol. 13, Issue. 1,

    Vernon, Anthony C. Natesan, Sridhar Modo, Mike and Kapur, Shitij 2011. Effect of Chronic Antipsychotic Treatment on Brain Structure: A Serial Magnetic Resonance Imaging Study with Ex Vivo and Postmortem Confirmation. Biological Psychiatry, Vol. 69, Issue. 10, p. 936.


Brain volume changes in schizophrenia: how do they arise? what do they mean?: A commentary on ‘Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings’ by Navari & Dazzan (2009)

  • D. A. Lewis (a1)
  • DOI:
  • Published online: 20 April 2009
Corresponding author
*Address for correspondence: D. A. Lewis, M.D., Departments of Psychiatry and Neuroscience, University of Pittsburgh, W1652 BST, 3811 O'Hara Street, Pittsburgh, PA15213, USA. (Email:
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SJ Borgwardt , PK McGuire , J Aston , U Gschwandtner , MO Pfluger , RD Stieglitz , EW Radue , A Riecher-Rossler (2008). Reductions in frontal, temporal and parietal volume associated with the onset of psychosis. Schizophrenia Research 106, 108114.

TD Cannon , K Cadenhead , B Cornblatt , SW Woods , J Addington , E Walker , LJ Seidman , D Perkins , M Tsuang , T McGlashan , R Heinssen (2008). Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Archives of General Psychiatry 65, 2837.

K-A Dorph-Petersen , JN Pierri , JM Perel , Z Sun , AR Sampson , DA Lewis (2005). The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: a comparison of haloperidol and olanzapine in macaque monkeys. Neuropsychopharmacology 30, 16491661.

GT Konopaske , KA Dorph-Petersen , JN Pierri , Q Wu , AR Sampson , DA Lewis (2007). Effect of chronic exposure to antipsychotic medication on cell numbers in the parietal cortex of macaque monkeys. Neuropsychopharmacology 32, 12161223.

GT Konopaske , K-A Dorph-Petersen , RA Sweet , JN Pierri , W Zhang , AR Sampson , DA Lewis (2008). Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeys. Biological Psychiatry 63, 759765.

S Navari , P Dazzan (2009). Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings. Psychological Medicine. Published online: 2 April 2009. doi:10.1017/S0033291709005315.

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Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
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