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Brain volume changes in schizophrenia: how do they arise? what do they mean?: A commentary on ‘Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings’ by Navari & Dazzan (2009)

  • D. A. Lewis (a1)
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Corresponding author
*Address for correspondence: D. A. Lewis, M.D., Departments of Psychiatry and Neuroscience, University of Pittsburgh, W1652 BST, 3811 O'Hara Street, Pittsburgh, PA 15213, USA. (Email: lewisda@upmc.edu)
References
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Borgwardt SJ, McGuire PK, Aston J, Gschwandtner U, Pfluger MO, Stieglitz RD, Radue EW, Riecher-Rossler A (2008). Reductions in frontal, temporal and parietal volume associated with the onset of psychosis. Schizophrenia Research 106, 108114.
Cannon TD, Cadenhead K, Cornblatt B, Woods SW, Addington J, Walker E, Seidman LJ, Perkins D, Tsuang M, McGlashan T, Heinssen R (2008). Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Archives of General Psychiatry 65, 2837.
Dorph-Petersen K-A, Pierri JN, Perel JM, Sun Z, Sampson AR, Lewis DA (2005). The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: a comparison of haloperidol and olanzapine in macaque monkeys. Neuropsychopharmacology 30, 16491661.
Konopaske GT, Dorph-Petersen KA, Pierri JN, Wu Q, Sampson AR, Lewis DA (2007). Effect of chronic exposure to antipsychotic medication on cell numbers in the parietal cortex of macaque monkeys. Neuropsychopharmacology 32, 12161223.
Konopaske GT, Dorph-Petersen K-A, Sweet RA, Pierri JN, Zhang W, Sampson AR, Lewis DA (2008). Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeys. Biological Psychiatry 63, 759765.
Navari S, Dazzan P (2009). Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings. Psychological Medicine. Published online: 2 April 2009. doi:10.1017/S0033291709005315.
Pierri JN, Chaudry AS, Woo T-U, Lewis DA (1999). Alterations in chandelier neuron axon terminals in the prefrontal cortex of schizophrenic subjects. American Journal of Psychiatry 156, 17091719.
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Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
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