Callahan, Brandy L. Simard, Martine Mouiha, Abderazzak Rousseau, François Laforce, Robert Hudon, Carol and Conde-Sala, J. Lluís 2017. Impact of Depressive Symptoms on Memory for Emotional Words in Mild Cognitive Impairment and Late-Life Depression. Journal of Alzheimer's Disease, Vol. 52, Issue. 2, p. 451.
Eriksson, Karin Hartelius, Lena and Saldert, Charlotta 2017. Participant characteristics and observed support in conversations involving people with communication disorders. International Journal of Speech-Language Pathology, p. 1.
Hankin, Benjamin L. Snyder, Hannah R. and Gulley, Lauren D. 2017. Developmental Psychopathology.
Naismith, Sharon L. and Mowszowski, Loren 2017. Cardiovascular Diseases and Depression.
Nilsson, J. Thomas, A. J. Stevens, L. H. McAllister-Williams, R. H. Ferrier, I. N. and Gallagher, P. 2017. The interrelationship between attentional and executive deficits in major depressive disorder. Acta Psychiatrica Scandinavica, Vol. 134, Issue. 1, p. 73.
Pantzar, Alexandra Atti, Anna Rita Fratiglioni, Laura Fastbom, Johan Bäckman, Lars and Laukka, Erika J. 2017. Cognitive performance in unipolar old-age depression: a longitudinal study. International Journal of Geriatric Psychiatry,
Polosan, M. Lemogne, C. Jardri, R. and Fossati, P. 2017. La cognition au cœur de la dépression. L'Encéphale, Vol. 42, Issue. 1, p. 1S3.
Rosano, Caterina Perera, Subashan Inzitari, Marco Newman, Anne B. Longstreth, William T. and Studenski, Stephanie 2017. Digit Symbol Substitution test and future clinical and subclinical disorders of cognition, mobility and mood in older adults. Age and Ageing,
Wang, Ya-li Yang, Shu-zhen Sun, Wei-li Shi, Yu-zhong and Duan, Hui-feng 2017. Altered functional interaction hub between affective network and cognitive control network in patients with major depressive disorder. Behavioural Brain Research, Vol. 298, p. 301.
Woo, Young Sup Rosenblat, Joshua D. Kakar, Ron Bahk, Won-Myong and McIntyre, Roger S. 2017. Cognitive Deficits as a Mediator of Poor Occupational Function in Remitted Major Depressive Disorder Patients. Clinical Psychopharmacology and Neuroscience, Vol. 14, Issue. 1, p. 1.
Zaninotto, Leonardo Solmi, Marco Veronese, Nicola Guglielmo, Riccardo Ioime, Lucia Camardese, Giovanni and Serretti, Alessandro 2017. A meta-analysis of cognitive performance in melancholic versus non-melancholic unipolar depression. Journal of Affective Disorders, Vol. 201, p. 15.
Zhang, Bing-Wei Xu, Jing and Chang, Yi 2017. The Effect of Aging in Inhibitory Control of Major Depressive Disorder Revealed by Event-Related Potentials. Frontiers in Human Neuroscience, Vol. 10,
Berntzen, Maiken Lied and Bystad, Martin 2017. Depression – a risk factor for dementia?. Scandinavian Psychologist, Vol. 2,
Boccia, Maddalena Acierno, Mauro and Piccardi, Laura 2017. Neuroanatomy of Alzheimer’s Disease and Late-Life Depression: A Coordinate-Based Meta-Analysis of MRI Studies. Journal of Alzheimer's Disease, Vol. 46, Issue. 4, p. 963.
Donoghue, Orna A. O’Hare, Celia King-Kallimanis, Bellinda and Kenny, Rose Anne 2017. Antidepressants are Independently Associated with Gait Deficits in Single and Dual Task Conditions. The American Journal of Geriatric Psychiatry, Vol. 23, Issue. 2, p. 189.
Hwang, J W Egorova, N Yang, X Q Zhang, W Y Chen, J Yang, X Y Hu, L J Sun, S Tu, Y and Kong, J 2017. Subthreshold depression is associated with impaired resting-state functional connectivity of the cognitive control network. Translational Psychiatry, Vol. 5, Issue. 11, p. e683.
Kvelde, Tasha Lord, Stephen R. Close, Jacqueline C.T. Reppermund, Simone Kochan, Nicole A. Sachdev, Perminder Brodaty, Henry and Delbaere, Kim 2017. Depressive symptoms increase fall risk in older people, independent of antidepressant use, and reduced executive and physical functioning. Archives of Gerontology and Geriatrics, Vol. 60, Issue. 1, p. 190.
Maes, Michael 2017. Mechanisms Underlying Neurocognitive Dysfunctions in Recurrent Major Depression. Medical Science Monitor, Vol. 21, p. 1535.
Roca, Miquel Monzón, Saray Vives, Margalida López-Navarro, Emilio Garcia-Toro, Mauro Vicens, Caterina Garcia-Campayo, Javier Harrison, John and Gili, Margalida 2017. Cognitive function after clinical remission in patients with melancholic and non-melancholic depression: A 6 month follow-up study. Journal of Affective Disorders, Vol. 171, p. 85.
Roca, Miquel López-Navarro, Emilio Monzón, Saray Vives, Margalida García-Toro, Mauro García-Campayo, Javier Harrison, John and Gili, Margalida 2017. Cognitive impairment in remitted and non-remitted depressive patients: A follow-up comparison between first and recurrent episodes. European Neuropsychopharmacology, Vol. 25, Issue. 11, p. 1991.
The cognitive impairment of older depressed patients with late- as opposed to early-onset illness may show important differences, in that patients with early onset may suffer predominantly from impaired episodic memory, and those with late onset mainly from reductions of executive function and processing speed.
We searched Medline and EMBASE as well as individual papers' reference lists for relevant publications, recording comparisons in neuropsychological test results between early-onset depression (EOD), late-onset depression (LOD) and healthy volunteers. Effect sizes are presented for cognitive domains, such as executive function, processing speed, episodic memory, semantic memory and mental state examination.
Patients with LOD showed greater reductions in processing speed and executive function than patients with EOD and controls. Both patient groups showed reduced function in all domains, except mental state, compared with controls.
Pronounced executive deficits are typical of the late-onset patients described in published studies, while episodic memory impairment is not specific to early-onset illness. Possible reasons and confounders are discussed.
This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Email your librarian or administrator to recommend adding this journal to your organisation's collection.
Full text views reflects the number of PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.
* Views captured on Cambridge Core between September 2016 - 21st September 2017. This data will be updated every 24 hours.