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Continuation therapy in endogenous depression controlled by changes in the TRH stimulation test

Published online by Cambridge University Press:  09 July 2009

C. Kirkegaard*
Affiliation:
Medical Department E and Psychiatric Department D, Frederiksberg Hospital, Copenhagen, Denmark
Eli Smith*
Affiliation:
Medical Department E and Psychiatric Department D, Frederiksberg Hospital, Copenhagen, Denmark
*
1Address for correspondence: Dr C. Kirkegaard, Medical Department E, Frederiksberg Hospital, DK-2000 Copenhagen, Denmark.
1Address for correspondence: Dr C. Kirkegaard, Medical Department E, Frederiksberg Hospital, DK-2000 Copenhagen, Denmark.

Synopsis

Thyrotropin response to thyrotropin-releasing hormone is impaired during endogenous depression and normalized between the depressive periods. Changes in the thyrotropin response to thyrotropin-releasing hormone were shown to be of predictive value and might be useful in the control of continuation therapy with antidepressants in patients with endogenous depression.

Type
Preliminary Communication
Copyright
Copyright © Cambridge University Press 1978

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References

Davis, J. M. (1976). Overview: maintenance therapy in psychiatry. II. Affective disorders. American Journal of Psychiatry 133, 113.Google ScholarPubMed
Kastin, A. J., Ehrensing, R. H., Schalch, D. S. & Anderson, M. S. (1972). Improvement in mental depression with decreased thyrotropin response after administration of thyrotropin-releasing hormone. Lancet ii, 740742.CrossRefGoogle Scholar
Kay, D. W. K., Fahy, T. & Garside, R. F. (1970). A seven-month double-blind trial of amitriptyline and diazepam in ECT-treated depressed patients. British Journal of Psychiatry 117, 667671.Google ScholarPubMed
Kirkegaard, C., Nørlem, N., Lauridsen, U. B. & Bjørum, N. (1975). Prognostic value of thyrotropin-releasing hormone stimulation test in endogenous depression. Acta Psychiatrica Scandinavica 52, 170177.CrossRefGoogle ScholarPubMed
Kirkegaard, C., Bjørum, N., Cohn, D., Faber, J., Lauridsen, U. B. & Nerup, J. (1977). Studies on the influence of biogenic amines and psychoactive drugs on the prognostic value of the TRH stimulation test in endogenous depression. Psychoneuroendocrinology, 2, 131136.CrossRefGoogle ScholarPubMed
Kirkegaard, C., Bjorum, N., Cohn, D. & Lauridsen, U. B. (1978). Thyrotropin-releasing hormone (TRH) stimulation test in manic-depressive illness. Archives of General Psychiatry (in the press).CrossRefGoogle Scholar
Mindham, R. H. S., Howland, C. & Shepherd, M. (1972). Continuation therapy with tricyclic antidepressants in depressive illness. Lancet ii, 854855.CrossRefGoogle Scholar
Pekary, A. E., Hershman, J. M. & Parlow, A. F. (1975). A sensitive and precise radioimmunoassay for human thyroid-stimulation hormone. Journal of Clinical Endocrinology and Metabolism 41, 676684.CrossRefGoogle Scholar
Prange, A. J., Wilson, I. C., Lara, P. P., Alltop, L. B. & Breese, G. R. (1972). Effects of thyrotropin-releasing hormone in depression. Lancet ii, 9991002.CrossRefGoogle Scholar
Prien, R. F., Klett, C. J. & Caffey, E. M. (1973). Lithium carbonate and imipramine in prevention of affective episodes. Archives of General Psychiatry 29, 420425.CrossRefGoogle ScholarPubMed
Quitkin, F., Rifkin, A. & Klein, D. F. (1976). Prophylaxis of affective disorders. Archives of General Psychiatry 33, 337341.CrossRefGoogle ScholarPubMed
Seager, C. P. & Bird, R. L. (1962). Imipramine with electrical treatment in depression - a controlled trial. Journal of Mental Science 108, 704707.CrossRefGoogle ScholarPubMed