Aas, Monica Andreassen, Ole A. Aminoff, Sofie R. Færden, Ann Romm, Kristin L. Nesvåg, Ragnar Berg, Akiah O. Simonsen, Carmen Agartz, Ingrid and Melle, Ingrid 2017. A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis. BMC Psychiatry, Vol. 16, Issue. 1,
Demmo, Christine Lagerberg, Trine Vik Aminoff, Sofie R Hellvin, Tone Kvitland, Levi R. Haatveit, Beathe Simonsen, Carmen Andreassen, Ole A Melle, Ingrid and Ueland, Torill 2017. Course of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study. Psychiatry Research,
Helle, Siri Ringen, Petter Andreas Melle, Ingrid Larsen, Tor-Ketil Gjestad, Rolf Johnsen, Erik Lagerberg, Trine Vik Andreassen, Ole A. Kroken, Rune Andreas Joa, Inge ten Velden Hegelstad, Wenche and Løberg, Else-Marie 2017. Cannabis use is associated with 3years earlier onset of schizophrenia spectrum disorder in a naturalistic, multi-site sample (N=1119). Schizophrenia Research, Vol. 170, Issue. 1, p. 217.
Hunt, Glenn E. Malhi, Gin S. Cleary, Michelle Lai, Harry Man Xiong and Sitharthan, Thiagarajan 2017. Prevalence of comorbid bipolar and substance use disorders in clinical settings, 1990–2015: Systematic review and meta-analysis. Journal of Affective Disorders, Vol. 206, p. 331.
Kvitland, Levi R. Melle, Ingrid Aminoff, Sofie R. Lagerberg, Trine V. Andreassen, Ole A. and Ringen, Petter A. 2017. Cannabis use in first-treatment bipolar I disorder: relations to clinical characteristics. Early Intervention in Psychiatry, Vol. 10, Issue. 1, p. 36.
Kvitland, Levi Røstad Ringen, Petter Andreas Aminoff, Sofie Ragnhild Demmo, Christine Hellvin, Tone Lagerberg, Trine Vik Andreassen, Ole Andreas and Melle, Ingrid 2017. Duration of untreated illness in first-treatment bipolar I disorder in relation to clinical outcome and cannabis use. Psychiatry Research, Vol. 246, p. 762.
Rentzsch, Johannes Stadtmann, Ada Montag, Christiane Kunte, Hagen Plöckl, Doris Hellweg, Rainer Gallinat, Jürgen Kronenberg, Golo and Jockers-Scherübl, Maria Christiane 2017. Attentional dysfunction in abstinent long-term cannabis users with and without schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, Vol. 266, Issue. 5, p. 409.
Steinan, Mette Kvisten Morken, Gunnar Lagerberg, Trine V. Melle, Ingrid Andreassen, Ole A. Vaaler, Arne E. and Scott, Jan 2017. Delayed sleep phase: An important circadian subtype of sleep disturbance in bipolar disorders. Journal of Affective Disorders, Vol. 191, p. 156.
Aas, Monica Pedersen, Geir Henry, Chantal Bjella, Thomas Bellivier, Frank Leboyer, Marion Kahn, Jean-Pierre Cohen, Renaud F. Gard, Sebastien Aminoff, Sofie R. Lagerberg, Trine V. Andreassen, Ole A. Melle, Ingrid and Etain, Bruno 2017. Psychometric properties of the Affective Lability Scale (54 and 18-item version) in patients with bipolar disorder, first-degree relatives, and healthy controls. Journal of Affective Disorders, Vol. 172, p. 375.
Aminoff, Sofie Ragnhild Tesli, Martin Bettella, Francesco Aas, Monica Lagerberg, Trine Vik Djurovic, Srdjan Andreassen, Ole A. and Melle, Ingrid 2017. Polygenic risk scores in bipolar disorder subgroups. Journal of Affective Disorders, Vol. 183, p. 310.
Fernández-Mondragón, Susana and Adan, Ana 2017. Personality in male patients with substance use disorder and/or severe mental illness. Psychiatry Research, Vol. 228, Issue. 3, p. 488.
Kvitland, Levi Roestad Melle, Ingrid Aminoff, Sofie Ragnhild Demmo, Christine Lagerberg, Trine Vik Andreassen, Ole Andreas and Ringen, Petter Andreas 2017. Continued cannabis use at one year follow up is associated with elevated mood and lower global functioning in bipolar I disorder. BMC Psychiatry, Vol. 15, Issue. 1,
Nesvåg, Ragnar Knudsen, Gun Peggy Bakken, Inger Johanne Høye, Anne Ystrom, Eivind Surén, Pål Reneflot, Anne Stoltenberg, Camilla and Reichborn-Kjennerud, Ted 2017. Substance use disorders in schizophrenia, bipolar disorder, and depressive illness: a registry-based study. Social Psychiatry and Psychiatric Epidemiology, Vol. 50, Issue. 8, p. 1267.
Schultz, Brian R. Rodriguez-Cabezas, Lisette Angres, Dan and Smith, Matthew J. 2017. Treatment Strategies for Cannabis Use in Schizophrenia. Current Treatment Options in Psychiatry, Vol. 2, Issue. 2, p. 168.
Zorrilla, I. Aguado, J. Haro, J. M. Barbeito, S. López Zurbano, S. Ortiz, A. López, P. and Gonzalez-Pinto, A. 2017. Cannabis and bipolar disorder: does quitting cannabis use during manic/mixed episode improve clinical/functional outcomes?. Acta Psychiatrica Scandinavica, Vol. 131, Issue. 2, p. 100.
Aas, Monica Aminoff, Sofie R. Vik Lagerberg, Trine Etain, Bruno Agartz, Ingrid Andreassen, Ole A. and Melle, Ingrid 2017. Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma. Psychiatry Research, Vol. 218, Issue. 1-2, p. 252.
Aas, Monica Haukvik, Unn K. Djurovic, Srdjan Tesli, Martin Athanasiu, Lavinia Bjella, Thomas Hansson, Lars Cattaneo, Annamaria Agartz, Ingrid Andreassen, Ole A. and Melle, Ingrid 2017. Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders. Journal of Psychiatric Research, Vol. 59, p. 14.
Brandt, C. L. Eichele, T. Melle, I. Sundet, K. Server, A. Agartz, I. Hugdahl, K. Jensen, J. and Andreassen, O. A. 2017. Working memory networks and activation patterns in schizophrenia and bipolar disorder: comparison with healthy controls. The British Journal of Psychiatry, Vol. 204, Issue. 4, p. 290.
Sepehrmanesh, Zahra Ahmadvand, Afshin and Moraveji, Alireza 2017. Comorbidity and Pattern of Substance Use in Hospitalized Psychiatric Patients. Iranian Red Crescent Medical Journal, Vol. 16, Issue. 7,
Stefanis, Nikos C. Dragovic, Milan Power, Brian D. Jablensky, Assen Castle, David and Morgan, Vera A. 2017. The effect of drug use on the age at onset of psychotic disorders in an Australian cohort. Schizophrenia Research, Vol. 156, Issue. 2-3, p. 211.
Schizophrenia and bipolar disorder have partly overlapping clinical profiles, which include an over-representation of substance-use behaviour. There are few previous studies directly comparing substance-use patterns in the two disorders. The objective of the present study was to compare the prevalence of substance use in schizophrenia and bipolar disorder, and investigate possible differences in pattern and frequency of use.
A total of 336 patients with schizophrenia or bipolar spectrum disorder from a catchment area-based hospital service were included in a cross-sectional study. In addition to thorough clinical assessments, patients were interviewed about drug-use history, habits and patterns of use. The prevalence and drug-use patterns were compared between groups.
Patients with bipolar disorder had higher rates of alcohol consumption, while schizophrenia patients more often used centrally stimulating substances, had more frequent use of non-alcoholic drugs and more often used more than one non-alcoholic drug. Single use of cannabis was more frequent in bipolar disorder.
The present study showed diagnosis-specific patterns of substance use in severe mental disorder. This suggests a need for more disease-specific treatment strategies, and indicates that substance use may be an important factor in studies of overlapping disease mechanisms.
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