Skip to main content
×
Home
    • Aa
    • Aa

Heterogeneity in cognitive functioning of schizophrenic patients evaluated by a lexical decision task

  • C. PASSERIEUX (a1), J. SEGUI (a1), C. BESCHE (a1), J. F. CHEVALIER (a1), D. WIDLÖCHER (a1) and M. C. HARDY-BAYLÉ (a1)...
    • Published online: 01 November 1997
Abstract

Background. The disorganization pattern in schizophrenia, which involves formal thought disorders, is thought to be correlated with a deficit in integrative processes of contextual information. We tested the hypothesis that thought disordered schizophrenics, unlike non-thought disordered schizophrenics, would present a deficit in the processing of the context during a task which involves these integrative processes.

Methods. A group of 22 schizophrenic patients diagnosed in accordance with DSM-III-R criteria and a group of 11 control subjects were compared using a semantic priming version of the lexical decision task. The experimental design used low-level structuration of verbal material to reveal the difficulty that schizophrenic patients encounter in using semantic regularities.

Results. A significant difference in priming effect was found between the three groups. Control subjects and non-thought disordered schizophrenics exhibit a priming effect for related word pairs when compared with unrelated pairs (respectively F(1,10)=17·7; P<0·002 and F(1,10)=14·5; P>0·003) but thought disordered schizophrenics did not (F(1,10)<1; NS).

Conclusions. This finding provides evidence for the cognitive heterogeneity of schizophrenic subjects. This absence of priming effect in thought-disordered schizophrenic subjects supports the hypothesis that these patients present a deficit in the post-lexical controlled information processing that permits the integration of semantic information.

Copyright
Corresponding author
Address for correspondence: Dr Christine Passerieux, Service de psychiatrie, Hôpital Richaud, 1, rue Richaud, 78011 Versailles Cédex, France.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 15 *
Loading metrics...

Abstract views

Total abstract views: 43 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 22nd October 2017. This data will be updated every 24 hours.