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Outreach and screening following the 2005 London bombings: usage and outcomes

Published online by Cambridge University Press:  09 March 2010

C. R. Brewin*
Affiliation:
Clinical, Educational and Health Psychology, University CollegeLondon, UK
N. Fuchkan
Affiliation:
Clinical, Educational and Health Psychology, University CollegeLondon, UK
Z. Huntley
Affiliation:
Clinical, Educational and Health Psychology, University CollegeLondon, UK
M. Robertson
Affiliation:
Traumatic Stress Clinic, Camden and Islington NHS Foundation Trust, London, UK
M. Thompson
Affiliation:
Traumatic Stress Clinic, Camden and Islington NHS Foundation Trust, London, UK
P. Scragg
Affiliation:
Traumatic Stress Clinic, Camden and Islington NHS Foundation Trust, London, UK
P. d'Ardenne
Affiliation:
Institute of Psychotrauma, East London NHS Foundation Trust, London, UK
A. Ehlers
Affiliation:
Centre for Anxiety Disorders and Trauma, Institute of Psychiatry, London, UK
*
*Address for correspondence: Dr C. R. Brewin, Clinical, Educational and Health Psychology, University College London, Gower Street, LondonWC1E 6BT, UK. (Email: c.brewin@ucl.ac.uk)
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Abstract

Background

Little is known about how to remedy the unmet mental health needs associated with major terrorist attacks, or what outcomes are achievable with evidence-based treatment. This article reports the usage, diagnoses and outcomes associated with the 2-year Trauma Response Programme (TRP) for those affected by the 2005 London bombings.

Method

Following a systematic and coordinated programme of outreach, the contact details of 910 people were obtained by the TRP. Of these, 596 completed a screening instrument that included the Trauma Screening Questionnaire (TSQ) and items assessing other negative responses. Those scoring ⩾6 on the TSQ, or endorsing other negative responses, received a detailed clinical assessment. Individuals judged to need treatment (n=217) received trauma-focused cognitive-behaviour therapy (TF-CBT) or eye movement desensitization and reprocessing (EMDR). Symptom levels were assessed pre- and post-treatment with validated self-report measures of post-traumatic stress disorder (PTSD) and depression, and 66 were followed up at 1 year.

Results

Case finding relied primarily on outreach rather than standard referral pathways such as primary care. The effect sizes achieved for treatment of DSM-IV PTSD exceeded those usually found in randomized controlled trials (RCTs) and gains were well maintained an average of 1 year later.

Conclusions

Outreach with screening, linked to the provision of evidence-based treatment, seems to be a viable method of identifying and meeting mental health needs following a terrorist attack. Given the failure of normal care pathways, it is a potentially important approach that merits further evaluation.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2010. The online version of this article is published within an Open Access environment subject to the conditions of the Creative Commons Attribution-NonCommercial-ShareAlike licence <http://creativecommons.org/licenses/by-nc-sa/2.5/>. The written permission of Cambridge University Press must be obtained for commercial re-use.

Introduction

Although it is well established that, following terrorist attacks, a minority of individuals develop a persistent mental health problem, most commonly post-traumatic stress disorder (PTSD; Call & Pfefferbaum, Reference Call and Pfefferbaum1999; Whalley & Brewin, Reference Whalley and Brewin2007; Neria et al. Reference Neria, Nandi and Galea2008; WTC Medical Working Group, 2008), the evidence base for planning an effective response is lacking. In the UK it has been assumed that those requiring specialist treatment will be catered for by referrals from general practitioners (GPs) to existing services, but the effectiveness or otherwise of this care pathway has never been investigated. Following the 1995 Oklahoma City bombing, direct victims with more serious disorders are reported to have been under-served in terms of screening, triage, referral to specialist services for established treatments, and subsequent monitoring (Pfefferbaum et al. Reference Pfefferbaum, North, Flynn, Norris and DeMartino2002). Similarly, the latest report of the World Trade Center Registry documents high rates of continuing mental health needs 7 years after the attacks of 11 September 2001 (WTC Medical Working Group, 2008). To overcome this failure to meet treatment needs, early and proactive outreach has been recommended (Turner et al. Reference Turner, Thompson and Rosser1989; Brewin, Reference Brewin2001), but never formally implemented. We report on the activity and outcomes associated with a clinically led programme set up immediately following the 2005 London bombings to test the feasibility of implementing outreach and screening linked to evidence-based treatment.

The London bombings consisted of a series of linked incidents that stretched over 17 days from 7 to 23 July 2005, including both successful and failed attempts to detonate bombs and the shooting of an innocent passenger on an underground train. The 7 July attack was the largest mass casualty event in the UK since World War Two, resulting in 775 casualties and 52 deaths, and there were substantial psychological effects on the population of London (Rubin et al. Reference Rubin, Brewin, Greenberg, Simpson and Wessely2005). Seven months later much of this distress was reduced, but a minority reported persistent stress reactions and behavioural changes, with 61% reporting that they saw the world differently as a result of the bombings (Rubin et al. Reference Rubin, Brewin, Greenberg, Hacker Hughes, Simpson and Wessely2007). The public mental health strategy, adopted in London for the first time, was to assume that elevated symptoms in the majority of the local population would not be long-lasting, to systematically locate and screen individuals directly involved in the bombings, and to offer specialist, National Institute for Clinical Excellence (NICE)-recommended interventions to those who were not recovering naturally. The Trauma Response Programme (TRP), funded by the Department of Health, ran from September 2005 to September 2007. It consisted of two elements: a dedicated four-person screening and assessment team and additional clinical psychology sessions in specialist post-traumatic stress centres. The 2-year programme was run by a multi-professional steering group and was responsible to a project board that monitored and approved all costs incurred.

To assess the need for outreach we report whether referrals for treatment came through the expected route (i.e. GPs), on the take-up of screening, and on the prevalence of disorders requiring treatment. Only one previous study has investigated the outcome of evidence-based treatment initiated within 3 months of a terrorist attack (Gillespie et al. Reference Gillespie, Duffy, Hackmann and Clark2002) and it is not known whether these gains are maintained over time. We therefore investigated the clinical outcomes achieved by the TRP by collecting pre-treatment, post-treatment and 1-year follow-up data, and comparing our outcomes with the results of published randomized controlled trials (RCTs) for PTSD.

Method

Design

The programme design has been described previously (Brewin et al. Reference Brewin, Scragg, Robertson, Thompson, d'Ardenne and Ehlers2008). This was a single-cohort study, as the ethical, financial and organizational constraints of mounting an immediate and unplanned-for post-disaster response, and also the desire to overcome barriers to treatment, precluded the use of control groups or of enrolling individuals in a research trial. Ethical approval was received from Barnet, Enfield and Haringey Local Research Ethics Committee (LREC) and informed consent was obtained for non-audit data.

Screening

Contact details of individuals known to have been involved in the bombings were available from a wide variety of sources including NHS Direct, hospitals, charitable relief funds, and the police. All GPs in the greater London area received two letters from the Department of Health alerting them to the likelihood of mental health problems following exposure to the London bombings, and to the existence of the programme. A media campaign advertised the programme and encouraged individuals to contact it. All individuals identified received a letter or telephone call and a brief two-page questionnaire containing screening questions to detect any current symptoms of psychopathology. Screening for PTSD used the Trauma Screening Questionnaire (TSQ; Brewin et al. Reference Brewin, Rose, Andrews, Green, Tata, McEvedy, Turner and Foa2002), which enquires about the presence of 10 PTSD symptoms in the past week. Responses to each item are either ‘Yes, at least twice’ or ‘No’. Previous research has demonstrated that it has excellent performance relative to other PTSD screening instruments and that endorsement of ⩾6 symptoms yields high levels of sensitivity and specificity (Brewin, Reference Brewin2005; Walters et al. Reference Walters, Bisson and Shepherd2007). Other screening questions used a similar ‘Yes/No’ format and included two validated depression items (Kroenke et al. Reference Kroenke, Spitzer and Williams2003) and three specially constructed questions asking about travel phobia and about increased smoking and drinking following exposure to the bombings. A final question asked whether respondents had had any other response to the bombings that concerned them.

Clinical assessment

Individuals screening positive on the TSQ or endorsing any of the additional screening items were invited to attend for a more detailed assessment that included the SCID-IP (First et al. Reference First, Spitzer, Gibbon and Williams1997). This longer clinical assessment determined suitability for trauma-focused treatment in terms of meeting criteria for a DSM-IV or ICD-10 disorder that was related to being exposed to the bombings and that was not resolving of its own accord. Conditions not meeting full diagnostic criteria were also eligible if they were persistent and were associated with significant distress or impairment. Based on the self-reported trajectory of symptoms, a clinical decision was made whether to refer for immediate treatment or to continue monitoring in the expectation that recovery would occur naturally. In the latter case, individuals were screened again at 3-, 6- and 9-monthly intervals.

Treatment

Consistent with recently published guidelines (NICE, 2005), two treatments for PTSD were used: trauma-focused cognitive-behaviour therapy (TF-CBT) and eye movement desensitization and reprocessing (EMDR). All lead clinicians of the participating treatment centres met monthly to ensure that treatments were provided with uniform quality and in strict adherence with these guidelines. Rather than working from specific treatment manuals, clinicians were required to implement the individual TF-CBT or EMDR protocols used in their specialist centre and received ongoing supervision from experienced trauma clinicians there. The most commonly used approach was TF-CBT (>80% of patients treated). A minority of patients received either a combination of TF-CBT and EMDR (∼10%) or EMDR only (<10%). People with other disorders received evidence-based interventions for that disorder, mainly TF-CBT. There were no restrictions on the number of sessions. Patients in each of the three centres completed the symptom items from the Post-traumatic Diagnostic Scale (PDS; Foa et al. Reference Foa, Cashman, Jaycox and Perry1997) and the Beck Depression Inventory (BDI; Beck et al. Reference Beck, Rush, Shaw and Emery1979) before treatment started and at subsequent sessions until treatment was finished. There are 17 items scored 0–3 on the PDS, yielding a possible range of 0–51, and 21 items scored 0–3 on the BDI, yielding a possible range of 0–63. Scores from the final session that a patient attended were used as post-treatment measures.

Follow-up

As part of a separate evaluation attempts were made to follow up as many individuals who had been referred to treatment within the programme as possible. Within the lifetime of the project, 101 were followed up. This subsample did not differ from the 248 originally referred for treatment in age, gender, ethnicity or symptom scores pre- and post-treatment (p>0.05). Of these 101 participants, 10 never entered treatment and 10 never completed treatment according to their therapist. Follow-up outcome measures were collected on 66 out of 81 individuals who completed treatment, the median time being 390 days after treatment ended (range 48–793 days).

Statistical analyses

Changes in the PDS and BDI were tested with ANOVA and t tests separately for the intention-to-treat and completer samples. There were two measures of effect size. In addition to Cohen's d (the difference between the pre-treatment and post-treatment means divided by their common standard deviation), we report an alternative, more conservative measure, which is the mean pre-post difference divided by the standard deviation of the mean difference. Reliable change (improvement beyond that expected by chance) and clinically significant change (reliable change, with patients additionally moving from being closer to the mean of a dysfunctional population at pre-treatment to being closer to the mean of a functional population at post-treatment) were calculated using the formulae of Jacobson & Truax (Reference Jacobson and Truax1991). Thresholds for the PDS were calculated from original validation data provided in Foa et al. (Reference Foa, Cashman, Jaycox and Perry1997), yielding for reliable change a fall of at least 8.04 and a cut-off between populations of 23.36. Corresponding thresholds for the BDI (reliable change 8.46, cut-off point 14.29) were taken from Seggar et al. (Reference Seggar, Lambert and Hansen2002). As the dysfunctional samples of Foa et al. and Seggar et al. had a mean PDS and BDI score that best matched our subsample with DSM-IV PTSD, indices were only applied to this group.

Results

Contact with the screening and assessment team

Figure 1 provides a flow diagram that illustrates how individuals involved in the bombings whose identity became known to the programme progressed through screening, assessment and treatment. The programme obtained contact information and sent screening materials to 910 adults, mostly within the first 6 months. Only 4.3% of these contacts were as a result of GP referrals. Contact information came mainly from lists of survivors held by NHS hospitals and clinics (41.7%), from police witness lists (12.0%), from other organizations involved in the response to the bombings such as the 7 July Assistance Centre and the Red Cross (27.1%), and from occupational health departments (4.8%). In addition, individuals self-referred (5.8%) or referred relatives and friends (3.3%) as a result of seeing information in the mass media.

Fig. 1. Flow of participants through screening and treatment.

Of this sample, 65.5% returned at least one screening questionnaire. The average age of the screened sample was 41.6 years (s.d.=12.2 years), and 45% were male. Although most had been involved in the bombings on 7 July, some had been present at the other key events in the period stretching up until 23 July. According to the questionnaire, 32.8% said they had been injured, 57.9% believed that they might have been injured or killed, 16.9% said that a family member or close friend was injured or killed, and 73.8% claimed to have personally witnessed the effect of one of the bombings.

Of the 596 who returned a screening questionnaire, 56.7% screened positive at the first or subsequent screening and received a detailed clinical assessment. The most common primary diagnosis was DSM-IV PTSD, often co-morbid with other disorders (n=149; 41%). In addition, a further 40 (11%) met criteria for ICD-10 PTSD but not DSM-IV PTSD (all cases of DSM-IV PTSD met criteria for ICD-10 PTSD). Other diagnoses included specific (travel) phobia (n=28; 7.7%), depression without PTSD (n=17; 4.7%), adjustment disorder (n=15; 4.1%), complicated grief (n=11; 3.0%) and generalized anxiety disorder (n=6; 1.7%). Data on the existence of previous mental disorder were available on 304 of those assessed and indicated that 16.1% had had a disorder.

In total, 304 people were known to the programme to be in need of treatment for psychological problems related to the London bombings. Being judged in need of treatment was unrelated to reporting a previous mental disorder [χ2(1, n=304)=1.61, n.s.]. Twenty-six were not referred, mainly because they did not want treatment at that time. Of the 278 people who were referred for psychological therapy, 30 were treated nearer to where they lived and were not assessed further. A total of 248 were referred to the three participating specialist post-traumatic stress centres. Of these 248, contact was lost prior to treatment with 31 patients, leaving 217 patients who entered treatment. Of these, 101 were men and 116 were women. Their average age was 40.6 years (range 22–71, s.d.=10.1 years). Self-identified ethnicity was White British, White Irish or White Other (69.7%), Black African, Black Caribbean or Black Other (4.6%), Asian Indian or Chinese (4.2%), and Other (8.4%); 13.4% did not indicate their ethnic background.

Treatment

The sample as a whole attended an average of 11.9 sessions (range 1–59, s.d.=9.9) and missed 1.9 sessions (range 0–15, s.d.=2.6). Twenty-eight (13%) patients dropped out or refused treatment after entering the treatment programme, leaving a sample of 189 who completed treatment. Reporting previous mental health disorder was unrelated to the number of sessions attended, or to change achieved on the PDS or BDI [largest t(175–203)=1.35, n.s.]. To enable comparisons to be made with the research literature, outcome data are presented separately for the sample as a whole (all diagnoses) and for those specifically meeting DSM-IV criteria for PTSD.

All diagnoses

Table 1 shows the scores on the PDS and BDI separately for the entire (intention-to-treat) sample, including those who dropped out, and the (completer) sample who received a full course of treatment. Intention-to-treat data were imputed from the last observation carried forward (LOCF), and an ANOVA on the PDS scores showed statistically highly significant improvement [F(1, 207)=455.8, p<0.001]. There was similar improvement on the BDI scores [F(1, 207)=261.8, p<0.001]. Table 1 also shows the substantial effect size for these treatment gains.

Table 1. Treatment outcome details for all diagnoses

PDS, Post-traumatic Diagnostic Scale; BDI, Beck Depression Inventory; s.d., standard deviation.

In the completer sample there was statistical evidence for somewhat greater improvement on the PDS [F(1, 180)=510.5, p<0.001], with a correspondingly larger treatment effect size. There was no statistically significant difference between scores at the end of treatment and at follow-up [t(61)=−1.67, p>0.05], indicating that treatment gains had been well maintained an average of 1 year later. Similar improvement was shown on the BDI [F(1, 181)=300.2, p<0.001]. There was no statistically significant difference between scores at the end of treatment and at follow-up [t(63)=−1.54, p>0.05], indicating that treatment gains had been well maintained over time.

To test whether treatment gains were more likely at the beginning of the programme, when they could have been reflecting a normal recovery process, a correlation was computed between the extent of improvement and the time elapsed since the bombings before receiving treatment. On average, treatment began 321.49 days after the bombings (s.d.=170.84, range=42–768 days). The correlations with time elapsed were small and non-significant for both the PDS [r(204)=−0.06] and the BDI [r(206)=−0.07], indicating that treatment was equally effective whether it was delivered early or late in the programme.

DSM-IV PTSD

Outcome data are presented in Table 2. In the intention-to-treat sample there was a statistically highly significant degree of improvement on the PDS [F(1, 124)=308.1, p<0.001]. Cohen's d was a very substantial 1.87. Reliable clinical improvement was shown by 76.0% of patients, and 62.4% showed clinically significant change. There was similarly a large improvement on the BDI scores [F(1, 124)=167.0, p<0.001], but with a somewhat lower treatment effect size. Reliable clinical improvement was shown by 71.2% of patients, and 53.6% showed clinically significant change.

Table 2. Treatment outcome details for DSM-IV post-traumatic stress disorder (PTSD)

PDS, Post-traumatic Diagnostic Scale; BDI, Beck Depression Inventory; s.d., standard deviation.

In the completer sample there was once again evidence for pronounced improvement in DSM-IV PTSD on the PDS [F(1, 103)=367.4, p<0.001]. Reliable clinical improvement was shown by 86.0% of patients, and 66.4% showed clinically significant change. There was no statistically significant difference between scores at the end of treatment and at follow-up [t(36)=−1.40, p>0.05], indicating that treatment gains had been well maintained over time. There was similarly pronounced improvement on the BDI scores [F(1, 103)=206.2, p<0.001], but again with a somewhat lower treatment effect size. Reliable clinical improvement was shown by 82.2% of patients, and 56.1% showed clinically significant change. Once again there was no statistically significant difference between scores at the end of treatment and at follow-up [t(38)=−1.00, p>0.05], indicating that treatment gains had been well maintained.

Discussion

Although general population samples show a steep reduction in post-traumatic symptoms after disasters and terrorism, researchers detailing the clinical response to those most directly affected have commented repeatedly on the level of persistent unmet mental health needs (Call & Pfefferbaum, Reference Call and Pfefferbaum1999; WTC Medical Working Group, 2008). The TRP was designed specifically to address this problem. However, as no reliable estimates or official figures have been published documenting the numbers directly affected by the London bombings, it is not possible to assess what proportion of these were apprised of the programme and what proportion of those who needed treatment received it.

Previous studies suggest that treatment was rare without prior experience of the mental health system (Stuber et al. Reference Stuber, Galea, Boscarino and Schlesinger2006) and that only a small minority of individuals initiate contact with treatment services themselves (Rosser et al. Reference Rosser, Dewar and Thompson1991). Our data confirmed people's reluctance to refer themselves, and worryingly suggested a failure of standard care pathways. Although all GPs in London were informed individually about the programme on more than one occasion, very few of those identified had been referred in this way.

Did this reflect a failure of the primary care pathway? Perhaps GPs referred their patients for treatment elsewhere? We were in contact with other local departments of clinical psychology in London and consider it very unlikely that patients were referred for NICE-approved treatment from other sources. It could also be argued that GPs would have made referrals given sufficient time. We suggest that there are three reasons why this is unlikely: first, international data generally indicate persistent high levels of unmet need after disasters (Pfefferbaum et al. Reference Pfefferbaum, North, Flynn, Norris and DeMartino2002; WTC Medical Working Group, 2008); second, there is evidence that in the UK recognition of PTSD by GPs tends to be poor (Ehlers et al. Reference Ehlers, Gene-Cos and Perrin2009); and third, qualitative responses given during the course of our study identified a high level of dissatisfaction with GPs (Brewin et al. Reference Brewin, Fuchkan and Huntley2009). This suggests that without the programme's efforts at outreach there would have been much greater levels of unmet need.

In this study 31% of those who came to the programme's attention, and 47% of those who were screened, were judged to need treatment. These figures are consistent with the finding that 30–40% of those exposed directly to a terrorist attack are likely to suffer from PTSD 2 years later (Whalley & Brewin, Reference Whalley and Brewin2007). Nevertheless, the fact that such a high proportion screened positive may have reflected a lack of representativeness in our sample. In addition to variation in the way in which people were referred to the programme, the great majority of individuals had been affected directly, either by being injured themselves or by witnessing others' injuries. Many were convinced they would die. All these experiences are established risk factors for developing difficulties such as PTSD.

The outcome data add to evidence from previous, smaller studies that established psychological treatment methods can substantially reduce PTSD (Duffy et al. Reference Duffy, Gillespie and Clark2007; Levitt et al. Reference Levitt, Malta, Martin, Davis and Cloitre2007) in those affected by terrorist attacks, and show for the first time that these gains are maintained at an average of 1 year follow-up. Reporting a previous mental health problem did not result in a poorer outcome, and those with travel phobia also responded very strongly to treatment (Handley et al. Reference Handley, Salkovskis and Ehlers2009). The easiest way of evaluating our outcomes against other studies is to restrict the comparison to RCTs of multi-session CBT for individuals with DSM-IV PTSD following adult trauma (excluding military veterans who are likely to have extended trauma and generally have poorer outcomes). Cahill et al. (Reference Cahill, Rothbaum, Resick, Follette, Foa, Keane, Friedman and Cohen2009) have tabulated within-group and between-group effect sizes from previous trials. Within-group effect sizes tend to be larger and provide the appropriate comparison for the data from this study. The weighted average of within-group effect sizes for intention-to-treat analyses in previous trials is 1.32, and for completer analyses is 1.73. Our own effect sizes of 1.87 and 2.11 support the effectiveness of the therapy provided.

It is important to acknowledge that a significant minority of individuals received far more treatment sessions than are generally recommended by NICE for the treatment of PTSD. This was in most cases due to prior trauma or pre-existing psychopathology that required more extensive intervention. It is well established that such factors increase the risk for PTSD following exposure to trauma (Brewin et al. Reference Brewin, Rose, Andrews, Green, Tata, McEvedy, Turner and Foa2000). Thus, post-disaster service planning needs to incorporate the likelihood that a minority of individuals will require a level of intervention that exceeds the usual recommendations for PTSD following a single trauma.

The study had several limitations, some of which reflect the requirement to mount an effective response to the immediate needs of the affected population, despite the absence of any established mechanism to fund additional clinical activity or research within the necessary time-frame. Among these limitations, the absence of a waiting list control group makes it difficult to establish with certainty that the good outcome was due to treatment rather than natural recovery. However, a previous RCT that used an outreach and screening approach in motor vehicle accident survivors showed that TF-CBT was superior to a waiting-list control (Ehlers et al. Reference Ehlers, Clark, Hackmann, McManus, Fennell, Herbert and Mayou2003). We have additionally shown that people treated later in the programme had the same good outcomes as people treated earlier. As the bulk of natural recovery following trauma usually occurs in the first 6–12 months (Helzer et al. Reference Helzer, Robins and McEvoy1987; Kessler et al. Reference Kessler, Sonnega, Bromet, Hughes and Nelson1995), it is highly unlikely that spontaneous improvement could account for the observed outcomes. Another limitation stems from the lack of any mechanism in current UK emergency planning to establish a comprehensive database of all those who are affected by a disaster. This may lead to foreign nationals who return home post-incident being overlooked, and necessarily restricts the generalizability of all data, including ours, that seek to assess post-disaster outcomes.

There is now sufficient evidence to anticipate substantial levels of unmet need for mental health care following terrorist incidents, unless additional resources are provided. Although screening post-trauma has not always been useful in a military context (Rona et al. Reference Rona, Jones, French, Hooper and Wessely2004), there have now been several implementations in civilian post-disaster settings such as the 11 September 2001 WTC attacks (Donahue et al. Reference Donahue, Jackson, Shear, Felton and Essock2006) and Hurricane Katrina (Hamblen et al. Reference Hamblen, Norris, Pietruszkiewicz, Gibson, Naturale and Louis2009). In both of these programmes screening was introduced at least 18 months post-disaster and without being linked to extensive outreach. Our data go further in suggesting that, in the context of a terrorist attack, early and systematic attempts at outreach and screening may be an effective way of identifying those who could benefit from treatment, and that outreach can be coordinated with existing or specially commissioned resources to increase access to effective therapy. Important unanswered questions remain, for example about whether the approach would be effective for disasters where there are high levels of infrastructure damage, or where large numbers of children or survivors lacking English as a first language are involved. More rigorous testing of screening and alternative approaches and more systematic methods of identifying those involved in an incident are now urgently required.

Acknowledgements

Funding was received from the Department of Health Forensic Mental Health Programme, and research support from Camden and Islington NHS Foundation Trust. Dr Ehlers is supported by the Wellcome Trust.

Declaration of Interest

None.

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Figure 0

Fig. 1. Flow of participants through screening and treatment.

Figure 1

Table 1. Treatment outcome details for all diagnoses

Figure 2

Table 2. Treatment outcome details for DSM-IV post-traumatic stress disorder (PTSD)

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