Skip to main content
×
Home
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 37
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Culbert, Kristen M. Racine, Sarah E. and Klump, Kelly L. 2016. Sex Differences in the Central Nervous System.


    Culbert, Kristen M. Racine, Sarah E. and Klump, Kelly L. 2016. Hormonal Factors and Disturbances in Eating Disorders. Current Psychiatry Reports, Vol. 18, Issue. 7,


    Schiller, Crystal Edler Johnson, Sarah L. Abate, Anna C. Schmidt, Peter J. and Rubinow, David R. 2016. Comprehensive Physiology.


    Culbert, Kristen M. Racine, Sarah E. and Klump, Kelly L. 2015. Research Review: What we have learned about the causes of eating disorders - a synthesis of sociocultural, psychological, and biological research. Journal of Child Psychology and Psychiatry, Vol. 56, Issue. 11, p. 1141.


    Hildebrandt, Britny A. Racine, Sarah E. Keel, Pamela K. Burt, S. Alexandra Neale, Michael Boker, Steven Sisk, Cheryl L. and Klump, Kelly L. 2015. The effects of ovarian hormones and emotional eating on changes in weight preoccupation across the menstrual cycle. International Journal of Eating Disorders, Vol. 48, Issue. 5, p. 477.


    Klump, K. L. Hildebrandt, B. A. O'Connor, S. M. Keel, P. K. Neale, M. Sisk, C. L. Boker, S. and Burt, S. A. 2015. Changes in genetic risk for emotional eating across the menstrual cycle: a longitudinal study. Psychological Medicine, Vol. 45, Issue. 15, p. 3227.


    Maranhão, Mara Fernandes Estella, Nara Mendes Cury, Maria Elisa Gisbert Amigo, Veruska Lastoria Picasso, Clarissa Mollinero Berberian, Arthur Campbell, Iain Schmidt, Ulrike and Claudino, Angélica Medeiros 2015. The effects of repetitive transcranial magnetic stimulation in obese females with binge eating disorder: a protocol for a double-blinded, randomized, sham-controlled trial. BMC Psychiatry, Vol. 15, Issue. 1,


    Murnen, Sarah K. and Smolak, Linda 2015. The Wiley Handbook of Eating Disorders.


    Abdulhay, Amir Benton, Noah A. Klingerman, Candice M. Krishnamoorthy, Kaila Brozek, Jeremy M. and Schneider, Jill E. 2014. Estrous cycle fluctuations in sex and ingestive behavior are accentuated by exercise or cold ambient temperatures. Hormones and Behavior, Vol. 66, Issue. 1, p. 135.


    Cao, Xuehong Xu, Pingwen Oyola, Mario G. Xia, Yan Yan, Xiaofeng Saito, Kenji Zou, Fang Wang, Chunmei Yang, Yongjie Hinton, Antentor Yan, Chunling Ding, Hongfang Zhu, Liangru Yu, Likai Yang, Bin Feng, Yuxin Clegg, Deborah J. Khan, Sohaib DiMarchi, Richard Mani, Shaila K. Tong, Qingchun and Xu, Yong 2014. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. Journal of Clinical Investigation, Vol. 124, Issue. 10, p. 4351.


    de Sá, Diana S. Ferreira Plein, Debora E. Schulz, André Oitzl, Melly S. Blumenthal, Terry D. and Schächinger, Hartmut 2014. Acoustic startle reactivity while processing reward-related food cues during food deprivation: Evidence from women in different menstrual cycle phases and men. Psychophysiology, Vol. 51, Issue. 2, p. 159.


    Haedt-Matt, Alissa A. Keel, Pamela K. Racine, Sarah E. Burt, S. Alexandra Hu, Jean Yueqin Boker, Steven Neale, Michael and Klump, Kelly L. 2014. Do emotional eating urges regulate affect? Concurrent and prospective associations and implications for risk models of binge eating. International Journal of Eating Disorders, Vol. 47, Issue. 8, p. 874.


    Harden, K. Paige Kretsch, Natalie Moore, Sarah R. and Mendle, Jane 2014. Descriptive review: Hormonal influences on risk for eating disorder symptoms during puberty and adolescence. International Journal of Eating Disorders, Vol. 47, Issue. 7, p. 718.


    Jappe, Leah M. Cao, Li Crosby, Ross D. Crow, Scott J. Peterson, Carol B. Le Grange, Daniel Engel, Scott G. and Wonderlich, Stephen A. 2014. Stress and eating disorder behavior in anorexia nervosa as a function of menstrual cycle status. International Journal of Eating Disorders, Vol. 47, Issue. 2, p. 181.


    Zander, Mary E. and De Young, Kyle P. 2014. Individual differences in negative affect and weekly variability in binge eating frequency. International Journal of Eating Disorders, Vol. 47, Issue. 3, p. 296.


    Babbs, R.K. Unger, E.L. and Corwin, R.L.W. 2013. 2-Hydroxyestradiol enhances binge onset in female rats and reduces prefrontal cortical dopamine in male rats. Hormones and Behavior, Vol. 63, Issue. 1, p. 88.


    Klump, Kelly L. 2013. Puberty as a critical risk period for eating disorders: A review of human and animal studies. Hormones and Behavior, Vol. 64, Issue. 2, p. 399.


    Klump, Kelly L. Keel, Pamela K. Burt, S. Alexandra Racine, Sarah E. Neale, Michael C. Sisk, Cheryl L. and Boker, Steven 2013. Ovarian hormones and emotional eating associations across the menstrual cycle: An examination of the potential moderating effects of body mass index and dietary restraint. International Journal of Eating Disorders, Vol. 46, Issue. 3, p. 256.


    Racine, Sarah E. Keel, Pamela K. Burt, S. Alexandra Sisk, Cheryl L. Neale, Michael Boker, Steven and Klump, Kelly L. 2013. Individual differences in the relationship between ovarian hormones and emotional eating across the menstrual cycle: A role for personality?. Eating Behaviors, Vol. 14, Issue. 2, p. 161.


    Schiller, Crystal Edler O'Hara, Michael W. Rubinow, David R. and Johnson, Alan Kim 2013. Estradiol modulates anhedonia and behavioral despair in rats and negative affect in a subgroup of women at high risk for postpartum depression. Physiology & Behavior, Vol. 119, p. 137.


    ×

Ovarian hormones and binge eating in bulimia nervosa

  • CRYSTAL EDLER (a1), SUSAN F. LIPSON (a2) and PAMELA K. KEEL (a1)
  • DOI: http://dx.doi.org/10.1017/S0033291706008956
  • Published online: 12 October 2006
Abstract

Background. Symptom fluctuation in bulimia nervosa (BN) is related to menstrual cycle phase. However, the relationship between bulimic symptoms and ovarian hormones (estrogens and progesterone) has not been examined directly in women with BN.

Method. Regularly menstruating women with DSM-IV BN (n=9) and regularly menstruating controls (n=8) collected hormone samples and recorded mood and bulimic symptoms daily for 35 consecutive days. Estradiol and progesterone were measured by radioimmunoassay. Within-subject analyses examined prospective longitudinal associations between changes in ovarian hormones and changes in binge frequency in women with BN. Analyses controlled for the possible influence of negative affect on binge frequency as well as the influence of progesterone when examining estradiol associations and the influence of estradiol when examining progesterone associations. Between-subject analyses examined whether women with BN were more likely to have disrupted hormonal profiles than controls.

Results. Increases in binge eating were significantly associated with both decreases in estradiol and increases in progesterone in BN women with intact menstrual cycles. Although BN women were more likely to have disrupted hormone profiles than controls, this difference did not reach statistical significance, and mean estradiol and progesterone levels did not differ between bulimic and control groups.

Conclusions. The results are consistent with those from experimental animal studies and suggest that decreases in estradiol and increases in progesterone may contribute to increases in binge eating. Ovarian hormone function represents a promising candidate for unraveling the neurobiological mechanisms of binge eating.

Copyright
Corresponding author
University of Iowa, E11 Seashore Hall, Iowa City, IA 52242, USA. (Email: pamela-keel@uiowa.edu)
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×